Distinct functions of POT1 proteins contribute to the regulation of telomerase recruitment to telomeres.

Gu, Peili; Jia, Shuting; Takasugi, Taylor; Tesmer, Valerie M; Nandakumar, Jayakrishnan; Chen, Yong; Chang, Sandy

Gu, Peili; Jia, Shuting; Takasugi, Taylor; Tesmer, Valerie M; Nandakumar, Jayakrishnan; Chen, Yong; Chang, Sandy.

Afiliação

Gu P; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, 06520, USA.
Jia S; Laboratory of Molecular Genetics of Aging and Tumor, School of Medicine, Kunming University Science and Technology, Kunming, 650500, China.
Takasugi T; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, 06520, USA.
Tesmer VM; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI, 48109, USA.
Nandakumar J; Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI, 48109, USA.
Chen Y; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, 200031, China.
Chang S; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, 06520, USA. schang@yale.edu.

Nat Commun ; 12(1): 5514, 2021 09 17.

Article em En | MEDLINE | ID: mdl-34535663

Assuntos

Proteínas de Ligação a DNA/metabolismo; Telomerase/metabolismo; Proteínas de Ligação a Telômeros/metabolismo; Telômero/metabolismo; Animais; Sistemas CRISPR-Cas/genética; Análise Mutacional de DNA; Camundongos; Ligação Proteica; Rad51 Recombinase/metabolismo; Sarcoma/patologia

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Telômero / Telomerase / Proteínas de Ligação a Telômeros / Proteínas de Ligação a DNA Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google