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Sequential Defects in Cardiac Lineage Commitment and Maturation Cause Hypoplastic Left Heart Syndrome.
Krane, Markus; Dreßen, Martina; Santamaria, Gianluca; My, Ilaria; Schneider, Christine M; Dorn, Tatjana; Laue, Svenja; Mastantuono, Elisa; Berutti, Riccardo; Rawat, Hilansi; Gilsbach, Ralf; Schneider, Pedro; Lahm, Harald; Schwarz, Sascha; Doppler, Stefanie A; Paige, Sharon; Puluca, Nazan; Doll, Sophia; Neb, Irina; Brade, Thomas; Zhang, Zhong; Abou-Ajram, Claudia; Northoff, Bernd; Holdt, Lesca M; Sudhop, Stefanie; Sahara, Makoto; Goedel, Alexander; Dendorfer, Andreas; Tjong, Fleur V Y; Rijlaarsdam, Maria E; Cleuziou, Julie; Lang, Nora; Kupatt, Christian; Bezzina, Connie; Lange, Rüdiger; Bowles, Neil E; Mann, Matthias; Gelb, Bruce D; Crotti, Lia; Hein, Lutz; Meitinger, Thomas; Wu, Sean; Sinnecker, Daniel; Gruber, Peter J; Laugwitz, Karl-Ludwig; Moretti, Alessandra.
Afiliação
  • Krane M; Department of Cardiovascular Surgery, Institute Insure (M.K., M.D., H.L., S.A.D., N.P., I.N., Z.Z., C.A.-A., R.L.),Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • Dreßen M; DZHK (German Centre for Cardiovascular Research)-partner site Munich Heart Alliance, Germany (M.K., A.D., C.K., R.L., T.M., D.S., K.-L.L., A.M.).
  • Santamaria G; Department of Cardiovascular Surgery, Institute Insure (M.K., M.D., H.L., S.A.D., N.P., I.N., Z.Z., C.A.-A., R.L.),Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • My I; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • Schneider CM; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • Dorn T; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • Laue S; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • Mastantuono E; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • Berutti R; German Heart Center Munich, and Institute of Human Genetics (E.M., R.B., T.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • Rawat H; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • Gilsbach R; Helmholtz Zentrum München, Neuherberg, Germany (E.M., R.B., T.M.).
  • Schneider P; German Heart Center Munich, and Institute of Human Genetics (E.M., R.B., T.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • Lahm H; Helmholtz Zentrum München, Neuherberg, Germany (E.M., R.B., T.M.).
  • Schwarz S; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • Doppler SA; Institute of Experimental and Clinical Pharmacology and Toxicology (R.G., P.S., L.H.), University of Freiburg, Germany.
  • Paige S; Institute for Cardiovascular Physiology, Goethe University, Frankfurt am Main, Germany (R.G.).
  • Puluca N; DZHK (German Centre for Cardiovascular Research)-partner site RheinMain, Frankfurt am Main, Germany (R.G.).
  • Doll S; Institute of Experimental and Clinical Pharmacology and Toxicology (R.G., P.S., L.H.), University of Freiburg, Germany.
  • Neb I; Department of Cardiovascular Surgery, Institute Insure (M.K., M.D., H.L., S.A.D., N.P., I.N., Z.Z., C.A.-A., R.L.),Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • Brade T; Center for Applied Tissue Engineering and Regenerative Medicine (CANTER), Munich University of Applied Sciences, Germany (S. Schwarz, S. Sudhop).
  • Zhang Z; Department of Cardiovascular Surgery, Institute Insure (M.K., M.D., H.L., S.A.D., N.P., I.N., Z.Z., C.A.-A., R.L.),Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • Abou-Ajram C; Cardiovascular Institute, Stanford University School of Medicine, CA (S.P., S.W.).
  • Northoff B; Department of Cardiovascular Surgery, Institute Insure (M.K., M.D., H.L., S.A.D., N.P., I.N., Z.Z., C.A.-A., R.L.),Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • Holdt LM; Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Martinsried, Germany (S.D., M.M.).
  • Sudhop S; Department of Cardiovascular Surgery, Institute Insure (M.K., M.D., H.L., S.A.D., N.P., I.N., Z.Z., C.A.-A., R.L.),Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • Sahara M; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • Goedel A; Department of Cardiovascular Surgery, Institute Insure (M.K., M.D., H.L., S.A.D., N.P., I.N., Z.Z., C.A.-A., R.L.),Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • Dendorfer A; Department of Cardiovascular Surgery, Institute Insure (M.K., M.D., H.L., S.A.D., N.P., I.N., Z.Z., C.A.-A., R.L.),Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • Tjong FVY; Institute of Laboratory Medicine (B.N., L.M.H.), University Hospital, LMU Munich, Germany.
  • Rijlaarsdam ME; Institute of Laboratory Medicine (B.N., L.M.H.), University Hospital, LMU Munich, Germany.
  • Cleuziou J; Center for Applied Tissue Engineering and Regenerative Medicine (CANTER), Munich University of Applied Sciences, Germany (S. Schwarz, S. Sudhop).
  • Lang N; Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden (M.S.).
  • Kupatt C; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • Bezzina C; DZHK (German Centre for Cardiovascular Research)-partner site Munich Heart Alliance, Germany (M.K., A.D., C.K., R.L., T.M., D.S., K.-L.L., A.M.).
  • Lange R; Walter-Brendel-Centre of Experimental Medicine (A.D.), University Hospital, LMU Munich, Germany.
  • Bowles NE; Heart Centre, Department of Clinical and Experimental Cardiology, Amsterdam UMC, University of Amsterdam, The Netherlands (F.V.Y.T., C.B.).
  • Mann M; Department of Pediatric Cardiology, Leiden University Medical Center, The Netherlands (M.E.R.).
  • Gelb BD; Department of Congenital and Paediatric Heart Surgery, Institute Insure (J.C.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • Crotti L; Department of Paediatric Cardiology and Congenital Heart Defects (N.L.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • Hein L; Department of Internal Medicine I, Cardiology (G.S., I.M., C.M.S., T.D., S.L., E.M., H.R., T.B., A.G., C.K., D.S., K.-L.L., A.M.), Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • Meitinger T; DZHK (German Centre for Cardiovascular Research)-partner site Munich Heart Alliance, Germany (M.K., A.D., C.K., R.L., T.M., D.S., K.-L.L., A.M.).
  • Wu S; Heart Centre, Department of Clinical and Experimental Cardiology, Amsterdam UMC, University of Amsterdam, The Netherlands (F.V.Y.T., C.B.).
  • Sinnecker D; Department of Cardiovascular Surgery, Institute Insure (M.K., M.D., H.L., S.A.D., N.P., I.N., Z.Z., C.A.-A., R.L.),Klinikum rechts der Isar, School of Medicine & Health, Technical University of Munich, Germany.
  • Gruber PJ; DZHK (German Centre for Cardiovascular Research)-partner site Munich Heart Alliance, Germany (M.K., A.D., C.K., R.L., T.M., D.S., K.-L.L., A.M.).
  • Laugwitz KL; Department of Pediatrics (Division of Cardiology), University of Utah School of Medicine, Salt Lake City (N.E.B.).
  • Moretti A; Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Martinsried, Germany (S.D., M.M.).
Circulation ; 144(17): 1409-1428, 2021 10 26.
Article em En | MEDLINE | ID: mdl-34694888
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome do Coração Esquerdo Hipoplásico / Organogênese Limite: Humans Idioma: En Revista: Circulation Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome do Coração Esquerdo Hipoplásico / Organogênese Limite: Humans Idioma: En Revista: Circulation Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha