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Demethylating therapy increases anti-CD123 CAR T cell cytotoxicity against acute myeloid leukemia.
El Khawanky, Nadia; Hughes, Amy; Yu, Wenbo; Myburgh, Renier; Matschulla, Tony; Taromi, Sanaz; Aumann, Konrad; Clarson, Jade; Vinnakota, Janaki Manoja; Shoumariyeh, Khalid; Miething, Cornelius; Lopez, Angel F; Brown, Michael P; Duyster, Justus; Hein, Lutz; Manz, Markus G; Hughes, Timothy P; White, Deborah L; Yong, Agnes S M; Zeiser, Robert.
Afiliação
  • El Khawanky N; Precision Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, SA, Australia.
  • Hughes A; School of Medicine, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia.
  • Yu W; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Myburgh R; Faculty of Biology, University of Freiburg, Freiburg, Germany.
  • Matschulla T; School of Medicine, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia.
  • Taromi S; Centre for Cancer Biology, SA Pathology and University of South Australia, Adelaide, SA, Australia.
  • Aumann K; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Comprehensive Cancer Center Zurich (CCCZ), Zurich, Switzerland.
  • Clarson J; Institute of Experimental and Clinical Pharmacology and Toxicology, Division II, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Vinnakota JM; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Shoumariyeh K; Faculty of Medical and Life Sciences, University Furtwangen, Villingen-Schwenningen, Germany.
  • Miething C; Department of Pathology, Institute for Clinical Pathology, University Medical Center Freiburg, Freiburg, Germany.
  • Lopez AF; Precision Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, SA, Australia.
  • Brown MP; Department of Haematology, Royal Adelaide Hospital, Adelaide, SA, Australia.
  • Duyster J; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Hein L; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Manz MG; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Hughes TP; School of Medicine, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia.
  • White DL; Centre for Cancer Biology, SA Pathology and University of South Australia, Adelaide, SA, Australia.
  • Yong ASM; School of Medicine, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia.
  • Zeiser R; Centre for Cancer Biology, SA Pathology and University of South Australia, Adelaide, SA, Australia.
Nat Commun ; 12(1): 6436, 2021 11 08.
Article em En | MEDLINE | ID: mdl-34750374
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Azacitidina / Leucemia Mieloide / Imunoterapia Adotiva / Ensaios Antitumorais Modelo de Xenoenxerto / Subunidade alfa de Receptor de Interleucina-3 / Anticorpos de Cadeia Única Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Austrália
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Azacitidina / Leucemia Mieloide / Imunoterapia Adotiva / Ensaios Antitumorais Modelo de Xenoenxerto / Subunidade alfa de Receptor de Interleucina-3 / Anticorpos de Cadeia Única Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Austrália