Strong and Specific Recognition of CAG/CTG Repeat DNA (5'-dWGCWGCW-3') by a Cyclic Pyrrole-Imidazole Polyamide.

Hirose, Yuki; Ohno, Tomo; Asamitsu, Sefan; Hashiya, Kaori; Bando, Toshikazu; Sugiyama, Hiroshi

Hirose, Yuki; Ohno, Tomo; Asamitsu, Sefan; Hashiya, Kaori; Bando, Toshikazu; Sugiyama, Hiroshi.

Afiliação

Hirose Y; Department of Chemistry, Graduate School of Science, Kyoto University, Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto, 606-8502, Japan.
Ohno T; Department of Chemistry, Graduate School of Science, Kyoto University, Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto, 606-8502, Japan.
Asamitsu S; Department of Chemistry, Graduate School of Science, Kyoto University, Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto, 606-8502, Japan.
Hashiya K; Present address: Department of Genomic Neurology, Institute of Molecular Embryology and Genetics, Kumamoto University, Honjo, Chuo-ku, Kumamoto, 860-0811, Japan.
Bando T; Department of Chemistry, Graduate School of Science, Kyoto University, Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto, 606-8502, Japan.
Sugiyama H; Department of Chemistry, Graduate School of Science, Kyoto University, Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto, 606-8502, Japan.

Chembiochem ; 23(2): e202100533, 2022 01 19.

Article em En | MEDLINE | ID: mdl-34796607

Assuntos

DNA/química; Imidazóis/química; Nylons/química; Pirróis/química; Sequências Repetitivas de Ácido Nucleico; Ressonância de Plasmônio de Superfície

Palavras-chave

CAG/CTG repeats; DNA recognition; pyrrole-imidazole polyamides; triplet repeats

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirróis / DNA / Sequências Repetitivas de Ácido Nucleico / Imidazóis / Nylons Idioma: En Revista: Chembiochem Assunto da revista: BIOQUIMICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Japão

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