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ATG12 deficiency results in intracellular glutamine depletion, abrogation of tumor hypoxia and a favorable prognosis in cancer.
Keulers, Tom G; Koch, Alexander; van Gisbergen, Marike W; Barbeau, Lydie M O; Zonneveld, Marijke I; de Jong, Monique C; Savelkouls, Kim G M; Wanders, Roel G; Bussink, Johan; Melotte, Veerle; Rouschop, Kasper M A.
Afiliação
  • Keulers TG; Department of Radiotherapy, Grow - School for Oncology and Developmental Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands.
  • Koch A; Department of Pathology, Grow - School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, Netherlands.
  • van Gisbergen MW; The M-Lab, Department of Precision Medicine, Grow - School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.
  • Barbeau LMO; Department of Radiotherapy, Grow - School for Oncology and Developmental Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands.
  • Zonneveld MI; Department of Radiotherapy, Grow - School for Oncology and Developmental Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands.
  • de Jong MC; Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Savelkouls KGM; Department of Radiotherapy, Grow - School for Oncology and Developmental Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands.
  • Wanders RG; MAASTRO Clinic, Maastricht, Netherlands.
  • Bussink J; Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Melotte V; Department of Pathology, Grow - School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, Netherlands.
  • Rouschop KMA; Department of Radiotherapy, Grow - School for Oncology and Developmental Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands.
Autophagy ; 18(8): 1898-1914, 2022 08.
Article em En | MEDLINE | ID: mdl-34904929

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína 12 Relacionada à Autofagia / Carcinoma de Células Escamosas de Cabeça e Pescoço / Glutamina / Neoplasias de Cabeça e Pescoço Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Autophagy Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína 12 Relacionada à Autofagia / Carcinoma de Células Escamosas de Cabeça e Pescoço / Glutamina / Neoplasias de Cabeça e Pescoço Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Autophagy Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Holanda