HEXA-018, a Novel Inducer of Autophagy, Rescues TDP-43 Toxicity in Neuronal Cells.

Lee, Shinrye; Jo, Myungjin; Lee, Hye Eun; Jeon, Yu-Mi; Kim, Seyeon; Kwon, Younghwi; Woo, Junghwa; Han, Shin; Mun, Ji Young; Kim, Hyung-Jun

Lee, Shinrye; Jo, Myungjin; Lee, Hye Eun; Jeon, Yu-Mi; Kim, Seyeon; Kwon, Younghwi; Woo, Junghwa; Han, Shin; Mun, Ji Young; Kim, Hyung-Jun.

Afiliação

Lee S; Dementia Research Group, Korea Brain Research Institute (KBRI), Daegu, South Korea.
Jo M; Dementia Research Group, Korea Brain Research Institute (KBRI), Daegu, South Korea.
Lee HE; Neural Circuit Research Group, Korea Brain Research Institute (KBRI), Daegu, South Korea.
Jeon YM; Dementia Research Group, Korea Brain Research Institute (KBRI), Daegu, South Korea.
Kim S; Dementia Research Group, Korea Brain Research Institute (KBRI), Daegu, South Korea.
Kwon Y; Department of Brain and Cognitive Sciences, DGIST, Daegu, South Korea.
Woo J; Dementia Research Group, Korea Brain Research Institute (KBRI), Daegu, South Korea.
Han S; Department of Brain and Cognitive Sciences, DGIST, Daegu, South Korea.
Mun JY; Dementia Research Group, Korea Brain Research Institute (KBRI), Daegu, South Korea.
Kim HJ; Hexa Pharmatec, Ansan-si, South Korea.

Front Pharmacol ; 12: 747975, 2021.

Article em En | MEDLINE | ID: mdl-34925009

Palavras-chave

ALS; TDP-43; autophagy; catechol; mitochondrial dysfunction

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Pharmacol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Coréia do Sul

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