Life-threatening Mycobacterium intracellulare pleuritis in an immunocompetent host: Case reports.
Medicine (Baltimore)
; 100(51): e28342, 2021 Dec 23.
Article
em En
| MEDLINE
| ID: mdl-34941139
ABSTRACT
RATIONALE Nontuberculous mycobacteria (NTM)-associated pleuritis is a very rare disease. Here, we describe 2 cases of life-threatening Mycobacterium intracellulare-associated pleuritis in immunocompetent hosts. PATIENT CONCERNS A 78-year-old man with sudden onset-onset dyspnea (case 1) and an 80-year-old man with cough, sputum and fever (case 2) presented to our emergency room. DIAGNOSES Both the patients were diagnosed with Mycobacterium intracellulare-associated pleuritis. INTERVENTION In case 1, the patient underwent intubation with mechanical ventilation due to hypoxemic respiratory failure. Daily azithromycin, rifampin and ethambutol, and intravenous amikacin 3 times a week was administered. In case 2, the patient received daily azithromycin, rifampin and ethambutol, and intravenous amikacin 3 times a week. OUTCOMES:
In case 1, after receiving NTM treatment for 14âmonths, NTM-associated pleuritis was cured, with radiologic improvement. In case 2, however, bronchopleural fistula was developed. Despite tube drainage, air leak continued. The patient refused surgical management and eventually died of respiratory failure. LESSONS Pleural effusion arising from NTM lung disease located in the subpleural area should be considered a possible cause of NTM-associated pleuritis. Drainage and a multidrug regimen are required to treat NTM, and surgical treatment should be considered when complications occur.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pleurisia
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Complexo Mycobacterium avium
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Micobactérias não Tuberculosas
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Infecções por Mycobacterium não Tuberculosas
Limite:
Aged
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Aged80
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Humans
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Male
Idioma:
En
Revista:
Medicine (Baltimore)
Ano de publicação:
2021
Tipo de documento:
Article