Molecular mechanisms in governing genomic stability and tumor suppression by the SETD2 H3K36 methyltransferase.

Lam, Ulysses Tsz Fung; Chen, Ee Sin

Lam, Ulysses Tsz Fung; Chen, Ee Sin.

Afiliação

Lam UTF; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Chen ES; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; National University Health System (NUHS), Singapore; NUS Center for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Integrative Sciences & Engineering Programme, National University of Singapore, Singapore. Electronic address: bchces@nus.edu.sg.

Int J Biochem Cell Biol ; 144: 106155, 2022 03.

Article em En | MEDLINE | ID: mdl-34990836

Assuntos

Histonas; Neoplasias; Animais; Carcinogênese/genética; Cromatina; Instabilidade Genômica; Histonas/genética; Histonas/metabolismo; Humanos; Lisina/metabolismo; Mamíferos/genética; Mamíferos/metabolismo; Metilação; Neoplasias/genética

Palavras-chave

Chromatin; DNA damage response; Epigenetics; Histone H3K36 methylation; SETD2; Set2

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Histonas / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Int J Biochem Cell Biol Assunto da revista: BIOQUIMICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Singapura

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