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VCP/p97 inhibitor CB-5083 modulates muscle pathology in a mouse model of VCP inclusion body myopathy.
Cheng, Cheng; Weiss, Lan; Leinonen, Henri; Shmara, Alyaa; Yin, Hong Z; Ton, Timothy; Do, Annie; Lee, Jonathan; Ta, Lac; Mohanty, Eshanee; Vargas, Jesse; Weiss, John; Palczewski, Krzysztof; Kimonis, Virginia.
Afiliação
  • Cheng C; Division of Genetics and Genomic Medicine, Dept. of Pediatrics, UC Irvine, Irvine, CA, USA.
  • Weiss L; Division of Genetics and Genomic Medicine, Dept. of Pediatrics, UC Irvine, Irvine, CA, USA.
  • Leinonen H; Gavin Herbert Eye Institute, and the Department of Ophthalmology, Center for Translational Vision Research, University of California, Irvine, Irvine, CA, USA.
  • Shmara A; Division of Genetics and Genomic Medicine, Dept. of Pediatrics, UC Irvine, Irvine, CA, USA.
  • Yin HZ; Department of Neurology, University of California, Irvine, Irvine, CA, USA.
  • Ton T; Division of Genetics and Genomic Medicine, Dept. of Pediatrics, UC Irvine, Irvine, CA, USA.
  • Do A; Division of Genetics and Genomic Medicine, Dept. of Pediatrics, UC Irvine, Irvine, CA, USA.
  • Lee J; Division of Genetics and Genomic Medicine, Dept. of Pediatrics, UC Irvine, Irvine, CA, USA.
  • Ta L; Division of Genetics and Genomic Medicine, Dept. of Pediatrics, UC Irvine, Irvine, CA, USA.
  • Mohanty E; Division of Genetics and Genomic Medicine, Dept. of Pediatrics, UC Irvine, Irvine, CA, USA.
  • Vargas J; Cleave Therapeutics, Inc., San Francisco, CA, USA.
  • Weiss J; Department of Neurology, University of California, Irvine, Irvine, CA, USA.
  • Palczewski K; Gavin Herbert Eye Institute, and the Department of Ophthalmology, Center for Translational Vision Research, University of California, Irvine, Irvine, CA, USA.
  • Kimonis V; Department of Physiology & Biophysics, University of California, Irvine, Irvine, CA, USA.
J Transl Med ; 20(1): 21, 2022 01 08.
Article em En | MEDLINE | ID: mdl-34998409
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Musculares Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Transl Med Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Musculares Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Transl Med Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos