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Spiropyrimidinetriones: a Class of DNA Gyrase Inhibitors with Activity against Mycobacterium tuberculosis and without Cross-Resistance to Fluoroquinolones.
Basarab, Gregory S; Ghorpade, Sandeep; Gibhard, Liezl; Mueller, Rudolf; Njoroge, Mathew; Peton, Nashied; Govender, Preshendren; Massoudi, Lisa M; Robertson, Gregory Thomas; Lenaerts, Anne J; Boshoff, Helena Ingrid; Joerss, Douglas; Parish, Tanya; Durand-Reville, Thomas F; Perros, Manos; Singh, Vinayak; Chibale, Kelly.
Afiliação
  • Basarab GS; Drug Discovery and Development Centre (H3D), Division of Clinical Pharmacology, University of Cape Towngrid.7836.a, Observatory, Cape Town, South Africa.
  • Ghorpade S; Drug Discovery and Development Centre (H3D), Department of Chemistry, University of Cape Towngrid.7836.a, Rondebosch, Cape Town, South Africa.
  • Gibhard L; Drug Discovery and Development Centre (H3D), Department of Chemistry, University of Cape Towngrid.7836.a, Rondebosch, Cape Town, South Africa.
  • Mueller R; Drug Discovery and Development Centre (H3D), Division of Clinical Pharmacology, University of Cape Towngrid.7836.a, Observatory, Cape Town, South Africa.
  • Njoroge M; Drug Discovery and Development Centre (H3D), Department of Chemistry, University of Cape Towngrid.7836.a, Rondebosch, Cape Town, South Africa.
  • Peton N; Drug Discovery and Development Centre (H3D), Division of Clinical Pharmacology, University of Cape Towngrid.7836.a, Observatory, Cape Town, South Africa.
  • Govender P; Drug Discovery and Development Centre (H3D), Department of Chemistry, University of Cape Towngrid.7836.a, Rondebosch, Cape Town, South Africa.
  • Massoudi LM; Drug Discovery and Development Centre (H3D), Department of Chemistry, University of Cape Towngrid.7836.a, Rondebosch, Cape Town, South Africa.
  • Robertson GT; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State Universitygrid.47894.36, Fort Collins, Colorado, USA.
  • Lenaerts AJ; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State Universitygrid.47894.36, Fort Collins, Colorado, USA.
  • Boshoff HI; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State Universitygrid.47894.36, Fort Collins, Colorado, USA.
  • Joerss D; Tuberculosis Research Section, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
  • Parish T; Infectious Disease Research Institute, Seattle, Washington, USA.
  • Durand-Reville TF; Center for Global Infectious Disease, Seattle Children's Research Institute, Seattle, Washington, USA.
  • Perros M; Infectious Disease Research Institute, Seattle, Washington, USA.
  • Singh V; Center for Global Infectious Disease, Seattle Children's Research Institute, Seattle, Washington, USA.
  • Chibale K; Entasis Therapeutics, Inc., Waltham, Massachusetts, USA.
Antimicrob Agents Chemother ; 66(4): e0219221, 2022 04 19.
Article em En | MEDLINE | ID: mdl-35266826
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tuberculose / Mycobacterium tuberculosis Limite: Humans Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2022 Tipo de documento: Article País de afiliação: África do Sul
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tuberculose / Mycobacterium tuberculosis Limite: Humans Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2022 Tipo de documento: Article País de afiliação: África do Sul