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SARS-CoV-2 BA.1 variant is neutralized by vaccine booster-elicited serum but evades most convalescent serum and therapeutic antibodies.
Lusvarghi, Sabrina; Pollett, Simon D; Neerukonda, Sabari Nath; Wang, Wei; Wang, Richard; Vassell, Russell; Epsi, Nusrat J; Fries, Anthony C; Agan, Brian K; Lindholm, David A; Colombo, Christopher J; Mody, Rupal; Ewers, Evan C; Lalani, Tahaniyat; Ganesan, Anuradha; Goguet, Emilie; Hollis-Perry, Monique; Coggins, Si'Ana A; Simons, Mark P; Katzelnick, Leah C; Wang, Gregory; Tribble, David R; Bentley, Lisa; Eakin, Ann E; Broder, Christopher C; Erlandson, Karl J; Laing, Eric D; Burgess, Timothy H; Mitre, Edward; Weiss, Carol D.
Afiliação
  • Lusvarghi S; Division of Viral Products, Office of Vaccine Research and Review, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA.
  • Pollett SD; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
  • Neerukonda SN; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD 20817, USA.
  • Wang W; Division of Viral Products, Office of Vaccine Research and Review, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA.
  • Wang R; Division of Viral Products, Office of Vaccine Research and Review, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA.
  • Vassell R; Division of Viral Products, Office of Vaccine Research and Review, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA.
  • Epsi NJ; Division of Viral Products, Office of Vaccine Research and Review, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA.
  • Fries AC; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
  • Agan BK; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD 20817, USA.
  • Lindholm DA; U.S. Air Force School of Aerospace Medicine, Wright-Patterson Air Force Base, Fairborn, OH 45433, USA.
  • Colombo CJ; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
  • Mody R; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD 20817, USA.
  • Ewers EC; Brooke Army Medical Center, Joint Base San Antonio-Fort Sam Houston, San Antonio, TX 78234, USA.
  • Lalani T; Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
  • Ganesan A; Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
  • Goguet E; Madigan Army Medical Center, Joint Base Lewis McChord, Tacoma, WA 98431, USA.
  • Hollis-Perry M; William Beaumont Army Medical Center, El Paso, TX 799218, USA.
  • Coggins SA; Fort Belvoir Community Hospital, Fort Belvoir, Fairfax county, VA 22060, USA, 22060.
  • Simons MP; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
  • Katzelnick LC; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD 20817, USA.
  • Wang G; Naval Medical Center Portsmouth, Portsmouth, VA 23708, USA.
  • Tribble DR; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
  • Bentley L; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD 20817, USA.
  • Eakin AE; Walter Reed National Military Medical Center, Bethesda, MD 20889, USA.
  • Broder CC; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD 20817, USA.
  • Erlandson KJ; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
  • Laing ED; Clinical Trials Center, Infectious Diseases Directorate, Naval Medical Research Center, Silver Spring, MD 20910, USA.
  • Burgess TH; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD 20817, USA.
  • Mitre E; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
  • Weiss CD; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
Sci Transl Med ; 14(645): eabn8543, 2022 05 18.
Article em En | MEDLINE | ID: mdl-35380448

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Limite: Humans Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Limite: Humans Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos