[Incidence and risk factors of ischemic stroke in patients with type 2 diabetes among urban workers in Beijing, China].
Beijing Da Xue Xue Bao Yi Xue Ban
; 54(2): 249-254, 2022 Apr 18.
Article
em Zh
| MEDLINE
| ID: mdl-35435187
ABSTRACT
OBJECTIVE:
To explore the incidence of ischemic stroke after the onset of type 2 diabetes, and further analyze the risk factors, so as to provide a basis for further research.METHODS:
The data were obtained from the database of the Beijing Urban Employee Basic Medical Insurance Database. The study used a prospective design to describe the incidence of ischemic stroke in patients with type 2 diabetes. In our study, these patients were followed up for seven years. Multivariate Logistic regression models were used to analyze the risk factors of ischemic stroke in patients with type 2 diabetes.RESULTS:
A total of 185 813 newly diagnosed type 2 diabetes patients were enrolled, with an average age of (58.5±13.2) years, and 49.0% of them were males. A total of 10 393 patients with newly diagnosed ischemic stroke occurred in 7 years, with a cumulative incidence of 5.6% and an incidence density of 8.1/1 000 person-years. Ischemic stroke occurred in all age groups in patients with type 2 diabetes. The cumulative incidence was 1.5% (95%CI 1.3%-1.6%) in group ≤44 years old, 3.6% (95%CI 3.4%-3.7%) in group 45-54 years old, 5.4% (95%CI 5.2%-5.5%) in group 55-64 years old, and 9.2% (95%CI 9.0%-9.4%) in group ≥65 years old, and the cumulative incidence increased with age (P < 0.05). Cumulative incidence rate of the males (6.8%, 95%CI 6.7%-7.0%) was higher than the females (4.4%, 95%CI 4.3%-4.6%). Among the patients < 80 years old, the cumulative incidence rate of the males was higher than that of the females in all the age groups. In the patients ≥80 years of age, the cumulative incidence was higher in the females (9.2%) than in the males (7.9%). Further analysis revealed that complications, such as coronary heart disease (OR=3.18, 95%CI 2.72-3.72), heart failure (OR=1.53, 95%CI 1.32-1.79) and kidney failure (OR=1.45, 95%CI 1.20-1.75) were associated with ischemic stroke in the patients with type 2 diabetes.CONCLUSION:
The incidence level of ischemic stroke in patients with type 2 diabetes is high. It is necessary to strengthen the management of risk factors in elderly patients, screen the complications of type 2 diabetes as early as possible, and take active preventive and control measures.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Acidente Vascular Cerebral
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Diabetes Mellitus Tipo 2
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AVC Isquêmico
Tipo de estudo:
Etiology_studies
/
Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
/
Middle aged
País/Região como assunto:
Asia
Idioma:
Zh
Revista:
Beijing Da Xue Xue Bao Yi Xue Ban
Assunto da revista:
MEDICINA
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
China