Polyglutamine Expansion in Huntingtin and Mechanism of DNA Damage Repair Defects in Huntington's Disease.

Pradhan, Subrata; Gao, Rui; Bush, Keegan; Zhang, Nan; Wairkar, Yogesh P; Sarkar, Partha S

Pradhan, Subrata; Gao, Rui; Bush, Keegan; Zhang, Nan; Wairkar, Yogesh P; Sarkar, Partha S.

Afiliação

Pradhan S; Department of Neurology, University of Texas Medical Branch, Galveston, TX, United States.
Gao R; Department of Neurology, University of Texas Medical Branch, Galveston, TX, United States.
Bush K; Department of Neuroscience, Cell Biology and Anatomy, University of Texas Medical Branch, Galveston, TX, United States.
Zhang N; Department of Neurology, Houston Methodist Research Institute, Houston, TX, United States.
Wairkar YP; Department of Neurology, University of Texas Medical Branch, Galveston, TX, United States.
Sarkar PS; Department of Neuroscience, Cell Biology and Anatomy, University of Texas Medical Branch, Galveston, TX, United States.

Front Cell Neurosci ; 16: 837576, 2022.

Article em En | MEDLINE | ID: mdl-35444517

Palavras-chave

Huntington's disease; defective DNA damage repair; huntingtin; microsatellite repeat expansion; polyglutamine repeat expansion; transcription-coupled DNA repair

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Cell Neurosci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google