miR-124-3p delivered by exosomes from heme oxygenase-1 modified bone marrow mesenchymal stem cells inhibits ferroptosis to attenuate ischemia-reperfusion injury in steatotic grafts.

Wu, Longlong; Tian, Xuan; Zuo, Huaiwen; Zheng, Weiping; Li, Xiang; Yuan, Mengshu; Tian, Xiaorong; Song, Hongli

Wu, Longlong; Tian, Xuan; Zuo, Huaiwen; Zheng, Weiping; Li, Xiang; Yuan, Mengshu; Tian, Xiaorong; Song, Hongli.

Afiliação

Wu L; School of Medicine, Nankai University, Tianjin, People's Republic of China.
Tian X; School of Medicine, Nankai University, Tianjin, People's Republic of China.
Zuo H; Tianjin First Central Hospital Clinic Institute, Tianjin Medical University, Tianjin, 300070, People's Republic of China.
Zheng W; Department of Organ Transplantation, Tianjin First Central Hospital, School of Medicine, Nankai University, No. 24 Fukang Road, Nankai District, Tianjin, 300192, People's Republic of China.
Li X; NHC Key Laboratory of Critical Care Medicine, Tianjin, 300192, People's Republic of China.
Yuan M; Tianjin First Central Hospital Clinic Institute, Tianjin Medical University, Tianjin, 300070, People's Republic of China.
Tian X; Tianjin First Central Hospital Clinic Institute, Tianjin Medical University, Tianjin, 300070, People's Republic of China.
Song H; Tianjin First Central Hospital Clinic Institute, Tianjin Medical University, Tianjin, 300070, People's Republic of China.

J Nanobiotechnology ; 20(1): 196, 2022 Apr 22.

Article em En | MEDLINE | ID: mdl-35459211

Assuntos

Exossomos; Ferroptose; Transplante de Fígado; Células-Tronco Mesenquimais; MicroRNAs; Traumatismo por Reperfusão; Animais; Exossomos/metabolismo; Ferroptose/fisiologia; Heme Oxigenase-1/genética; Heme Oxigenase-1/metabolismo; Doadores Vivos; Masculino; Células-Tronco Mesenquimais/metabolismo; MicroRNAs/genética; MicroRNAs/metabolismo; Ratos; Traumatismo por Reperfusão/metabolismo; Traumatismo por Reperfusão/prevenção & controle

Palavras-chave

Bone marrow mesenchymal stem cells; Exosomes; Ferroptosis; Heme oxygenase oxygen-1; Ischemiareperfusion injury; Liver transplantation; STEAP3; miR-124-3p

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Traumatismo por Reperfusão / Transplante de Fígado / MicroRNAs / Exossomos / Células-Tronco Mesenquimais / Ferroptose Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Nanobiotechnology Ano de publicação: 2022 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google