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A fluorogenic probe for granzyme B enables in-biopsy evaluation and screening of response to anticancer immunotherapies.
Scott, Jamie I; Mendive-Tapia, Lorena; Gordon, Doireann; Barth, Nicole D; Thompson, Emily J; Cheng, Zhiming; Taggart, David; Kitamura, Takanori; Bravo-Blas, Alberto; Roberts, Edward W; Juarez-Jimenez, Jordi; Michel, Julien; Piet, Berber; de Vries, I Jolanda; Verdoes, Martijn; Dawson, John; Carragher, Neil O; Connor, Richard A O'; Akram, Ahsan R; Frame, Margaret; Serrels, Alan; Vendrell, Marc.
Afiliação
  • Scott JI; Centre for Inflammation Research, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK.
  • Mendive-Tapia L; Centre for Inflammation Research, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK.
  • Gordon D; Centre for Inflammation Research, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK.
  • Barth ND; Centre for Inflammation Research, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK.
  • Thompson EJ; Centre for Inflammation Research, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK.
  • Cheng Z; Centre for Inflammation Research, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK.
  • Taggart D; Centre for Inflammation Research, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK.
  • Kitamura T; MRC Centre for Reproductive Health, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK.
  • Bravo-Blas A; Cancer Research UK Beatson Institute, Glasgow, UK.
  • Roberts EW; Cancer Research UK Beatson Institute, Glasgow, UK.
  • Juarez-Jimenez J; EaStChem School of Chemistry, Joseph Black Building, The University of Edinburgh, Edinburgh, UK.
  • Michel J; EaStChem School of Chemistry, Joseph Black Building, The University of Edinburgh, Edinburgh, UK.
  • Piet B; Department of Pulmonary Diseases, Radboud University Medical Centre, Nijmegen, Netherlands.
  • de Vries IJ; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, Netherlands.
  • Verdoes M; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, Netherlands.
  • Dawson J; Cancer Research UK Edinburgh Centre, The University of Edinburgh, Edinburgh, UK.
  • Carragher NO; Cancer Research UK Edinburgh Centre, The University of Edinburgh, Edinburgh, UK.
  • Connor RAO; Centre for Inflammation Research, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK.
  • Akram AR; Centre for Inflammation Research, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK.
  • Frame M; Cancer Research UK Edinburgh Centre, The University of Edinburgh, Edinburgh, UK.
  • Serrels A; Centre for Inflammation Research, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK.
  • Vendrell M; Centre for Inflammation Research, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK. marc.vendrell@ed.ac.uk.
Nat Commun ; 13(1): 2366, 2022 05 02.
Article em En | MEDLINE | ID: mdl-35501326
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoterapia / Neoplasias Pulmonares Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoterapia / Neoplasias Pulmonares Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido