Perinatal factors influence on the neurocognitive development of children born small for gestational age (SGA) during the first 2 years of life.
Endocrinol Diabetes Nutr (Engl Ed)
; 69(4): 271-278, 2022 Apr.
Article
em En
| MEDLINE
| ID: mdl-35570139
ABSTRACT
BACKGROUND AND OBJECTIVE:
Children born small for gestational age (SGA) show higher risk of neurodevelopmental and cognitive abnormalities. The objective of this study is to determine in children born SGA the neurodevelopment during the first 2 years of life and to establish the influence of anthropometric data, gestational age, multiple gestation and perinatal factors. PATIENTS ANDMETHOD:
Observational, prospective, descriptive and analytical study of the neurocognitive assessment performed, with Brunet-Lézine test, on SGA children (nâ¯=â¯91) from 3 to 24 months of age, comparing with own controls.RESULTS:
Ninety-one SGA children, 47% girls, 83.5% single pregnancies; mean gestational age 37.7 weeks (standard deviation (SD) 2.1). Weight at birth 2053â¯g (SD 433.1), length 43.9â¯cm (SD 2.6) and head circumference 31.7â¯cm (SD 1.7). The SGA population shows significantly lower neurodevelopment than the control population, with a tendency to improve during the first 2 years of life. There are no differences by sex. SGA children born to multiple gestations have lower neurodevelopment only during the first year of life. There is a direct and positive correlation between weight, length and head circumference with neurocognitive development at 6, 9, 12 and 18 months. Gestational age correlated with better neurodevelopment at 3 and 6 months.CONCLUSIONS:
Children born SGA present lower neurodevelopment than the control population. A greater impact on weight, length, and head circumference at birth is correlated with poorer neurocognitive development. Multiparity does not show significant influence on neurodevelopment evolution.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Recém-Nascido Pequeno para a Idade Gestacional
/
Retardo do Crescimento Fetal
Tipo de estudo:
Observational_studies
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Risk_factors_studies
Limite:
Child
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Child, preschool
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Female
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Humans
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Infant
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Male
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Newborn
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Pregnancy
Idioma:
En
Revista:
Endocrinol Diabetes Nutr (Engl Ed)
Ano de publicação:
2022
Tipo de documento:
Article