Serum hemato-immunological biomarkers associated with increased COVID-19 mortality in the Latino population.
Biomark Med
; 16(10): 799-810, 2022 07.
Article
em En
| MEDLINE
| ID: mdl-35574808
ABSTRACT
Introduction:
COVID-19 hospitalizations and deaths have raised the need of identifying prognostic factors for medical decision-making.Methods:
Observational, retrospective study analyzing 191 COVID-19 patients' serum inflammatory biomarkers.Results:
The median age was 48.7 ± 12.7 years, 75.9% being men. Overweight/obesity was the most common comorbidity in 83.8% of patients. 44.5% had moderate disease followed by 43.5% with severe disease. The mean percentage of pulmonary damage was 53.4% ± 28.7. Serum leukocyte-to-lymphocyte ratio >7.7, neutrophil-to-lymphocyte ratio >10, platelet-to-lymphocyte ratio ≥250 and nutritional index <362 all were independent mortality predictors for COVID-19.Conclusions:
A leukocyte-to-lymphocyte ratio >7.7 as well as a nutritional index <362 at hospitalization were independently associated with an increased mortality.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
COVID-19
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Biomark Med
Assunto da revista:
BIOQUIMICA
/
MEDICINA
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
México