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Design of a Randomized, Placebo-Controlled, Phase 3 Trial of Tofersen Initiated in Clinically Presymptomatic SOD1 Variant Carriers: the ATLAS Study.
Benatar, Michael; Wuu, Joanne; Andersen, Peter M; Bucelli, Robert C; Andrews, Jinsy A; Otto, Markus; Farahany, Nita A; Harrington, Elizabeth A; Chen, Weiping; Mitchell, Adele A; Ferguson, Toby; Chew, Sheena; Gedney, Liz; Oakley, Sue; Heo, Jeong; Chary, Sowmya; Fanning, Laura; Graham, Danielle; Sun, Peng; Liu, Yingying; Wong, Janice; Fradette, Stephanie.
Afiliação
  • Benatar M; Department of Neurology, University of Miami, 1120 NW 14th Street, Clinical Research Building, Miami, FL, 33136, USA. mbenatar@med.miami.edu.
  • Wuu J; Department of Neurology, University of Miami, 1120 NW 14th Street, Clinical Research Building, Miami, FL, 33136, USA.
  • Andersen PM; Department of Clinical Science, Neurosciences, Umeå University, Umeå, Sweden.
  • Bucelli RC; Washington University School of Medicine, St. Louis, MO, USA.
  • Andrews JA; The Neurological Institute, Columbia University Irving Medical Center, New York, NY, USA.
  • Otto M; Department of Neurology, Martin Luther University, Halle-Wittenberg, Halle (Saale), Germany.
  • Farahany NA; Duke University School of Law, Durham, NC, USA.
  • Harrington EA; Columbia University Irving Medical Center, New York, NY, USA.
  • Chen W; Biogen, 225 Binney Street, Cambridge, MA, 02142, USA.
  • Mitchell AA; Biogen, 225 Binney Street, Cambridge, MA, 02142, USA.
  • Ferguson T; Biogen, 225 Binney Street, Cambridge, MA, 02142, USA.
  • Chew S; Biogen, 225 Binney Street, Cambridge, MA, 02142, USA.
  • Gedney L; Biogen, 225 Binney Street, Cambridge, MA, 02142, USA.
  • Oakley S; Biogen, 225 Binney Street, Cambridge, MA, 02142, USA.
  • Heo J; Biogen, 225 Binney Street, Cambridge, MA, 02142, USA.
  • Chary S; Biogen, 225 Binney Street, Cambridge, MA, 02142, USA.
  • Fanning L; Biogen, 225 Binney Street, Cambridge, MA, 02142, USA.
  • Graham D; Biogen, 225 Binney Street, Cambridge, MA, 02142, USA.
  • Sun P; Biogen, 225 Binney Street, Cambridge, MA, 02142, USA.
  • Liu Y; Biogen, 225 Binney Street, Cambridge, MA, 02142, USA.
  • Wong J; Biogen, 225 Binney Street, Cambridge, MA, 02142, USA.
  • Fradette S; Biogen, 225 Binney Street, Cambridge, MA, 02142, USA. Stephanie.fradette@biogen.com.
Neurotherapeutics ; 19(4): 1248-1258, 2022 07.
Article em En | MEDLINE | ID: mdl-35585374
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Neurodegenerativas / Esclerose Lateral Amiotrófica Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Revista: Neurotherapeutics Assunto da revista: NEUROLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Neurodegenerativas / Esclerose Lateral Amiotrófica Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Revista: Neurotherapeutics Assunto da revista: NEUROLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos