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Altered splicing of ATG16-L1 mediates acquired resistance to tyrosine kinase inhibitors of EGFR by blocking autophagy in non-small cell lung cancer.
Hatat, Anne-Sophie; Benoit-Pilven, Clara; Pucciarelli, Amélie; de Fraipont, Florence; Lamothe, Lucie; Perron, Pascal; Rey, Amandine; Levra, Matteo Giaj; Toffart, Anne-Claire; Auboeuf, Didier; Eymin, Beatrice; Gazzeri, Sylvie.
Afiliação
  • Hatat AS; Team "RNA Splicing, Cell Signaling and Response to Therapies", Institute for Advanced Biosciences (IAB), INSERM U1209, CNRS UMR 5309, Grenoble Alpes University, France.
  • Benoit-Pilven C; Laboratory of Biology and Modelling of the Cell, Univ Lyon, ENS de Lyon, Univ Claude Bernard, CNRS UMR 5239, INSERM U1210, Lyon, France.
  • Pucciarelli A; Team "RNA Splicing, Cell Signaling and Response to Therapies", Institute for Advanced Biosciences (IAB), INSERM U1209, CNRS UMR 5309, Grenoble Alpes University, France.
  • de Fraipont F; Team "RNA Splicing, Cell Signaling and Response to Therapies", Institute for Advanced Biosciences (IAB), INSERM U1209, CNRS UMR 5309, Grenoble Alpes University, France.
  • Lamothe L; Molecular Genetic Unit, Grenoble-Alpes University Hospital, France.
  • Perron P; Team "RNA Splicing, Cell Signaling and Response to Therapies", Institute for Advanced Biosciences (IAB), INSERM U1209, CNRS UMR 5309, Grenoble Alpes University, France.
  • Rey A; Team "RNA Splicing, Cell Signaling and Response to Therapies", Institute for Advanced Biosciences (IAB), INSERM U1209, CNRS UMR 5309, Grenoble Alpes University, France.
  • Levra MG; Laboratory of Biology and Modelling of the Cell, Univ Lyon, ENS de Lyon, Univ Claude Bernard, CNRS UMR 5239, INSERM U1210, Lyon, France.
  • Toffart AC; Team "RNA Splicing, Cell Signaling and Response to Therapies", Institute for Advanced Biosciences (IAB), INSERM U1209, CNRS UMR 5309, Grenoble Alpes University, France.
  • Auboeuf D; Thoracic Oncology Unit, Grenoble-Alpes University Hospital, France.
  • Eymin B; Team "RNA Splicing, Cell Signaling and Response to Therapies", Institute for Advanced Biosciences (IAB), INSERM U1209, CNRS UMR 5309, Grenoble Alpes University, France.
  • Gazzeri S; Thoracic Oncology Unit, Grenoble-Alpes University Hospital, France.
Mol Oncol ; 16(19): 3490-3508, 2022 10.
Article em En | MEDLINE | ID: mdl-35593080
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Mol Oncol Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: França
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Mol Oncol Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: França