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Engineered Cas12i2 is a versatile high-efficiency platform for therapeutic genome editing.
McGaw, Colin; Garrity, Anthony J; Munoz, Gabrielle Z; Haswell, Jeffrey R; Sengupta, Sejuti; Keston-Smith, Elise; Hunnewell, Pratyusha; Ornstein, Alexa; Bose, Mishti; Wessells, Quinton; Jakimo, Noah; Yan, Paul; Zhang, Huaibin; Alfonse, Lauren E; Ziblat, Roy; Carte, Jason M; Lu, Wei-Cheng; Cerchione, Derek; Hilbert, Brendan; Sothiselvam, Shanmugapriya; Yan, Winston X; Cheng, David R; Scott, David A; DiTommaso, Tia; Chong, Shaorong.
Afiliação
  • McGaw C; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • Garrity AJ; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • Munoz GZ; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • Haswell JR; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • Sengupta S; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • Keston-Smith E; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • Hunnewell P; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • Ornstein A; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • Bose M; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • Wessells Q; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • Jakimo N; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • Yan P; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • Zhang H; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • Alfonse LE; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • Ziblat R; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • Carte JM; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • Lu WC; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • Cerchione D; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • Hilbert B; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • Sothiselvam S; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • Yan WX; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • Cheng DR; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • Scott DA; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
  • DiTommaso T; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA. tditommaso@arbor.bio.
  • Chong S; Arbor Biotechnologies, 20 Acorn Park Drive, Tower 500, Cambridge, MA, USA.
Nat Commun ; 13(1): 2833, 2022 05 20.
Article em En | MEDLINE | ID: mdl-35595757

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistemas CRISPR-Cas / Edição de Genes Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistemas CRISPR-Cas / Edição de Genes Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos