Proteomic phenotype of cerebral organoids derived from autism spectrum disorder patients reveal disrupted energy metabolism, cellular components, and biological processes.

Ilieva, Mirolyuba; Aldana, Blanca Irene; Vinten, Kasper Tore; Hohmann, Sonja; Woofenden, Thomas William; Lukjanska, Renate; Waagepetersen, Helle S; Michel, Tanja Maria

Ilieva, Mirolyuba; Aldana, Blanca Irene; Vinten, Kasper Tore; Hohmann, Sonja; Woofenden, Thomas William; Lukjanska, Renate; Waagepetersen, Helle S; Michel, Tanja Maria.

Afiliação

Ilieva M; Department of Psychiatry, Department of Clinical Research, University of Southern Denmark, Odense, Denmark. mirolyubasi@dcm.aau.dk.
Aldana BI; Psychiatry in the Region of Southern Denmark, Odense University Hospital, Odense, Denmark. mirolyubasi@dcm.aau.dk.
Vinten KT; Center for RNA Medicine, Department of Clinical Medicine, Aalborg University, Copenhagen SV, Denmark. mirolyubasi@dcm.aau.dk.
Hohmann S; Neurometabolism Research Group, Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Woofenden TW; Neurometabolism Research Group, Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Lukjanska R; Department of Psychiatry, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
Waagepetersen HS; Psychiatry in the Region of Southern Denmark, Odense University Hospital, Odense, Denmark.
Michel TM; Neurometabolism Research Group, Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Mol Psychiatry ; 27(9): 3749-3759, 2022 09.

Article em En | MEDLINE | ID: mdl-35618886

Assuntos

Transtorno do Espectro Autista; Fenômenos Biológicos; Humanos; Organoides; Transtorno do Espectro Autista/genética; Proteômica; Proteoma/genética; Fenótipo; Metabolismo Energético

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenômenos Biológicos / Transtorno do Espectro Autista Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Mol Psychiatry Assunto da revista: BIOLOGIA MOLECULAR / PSIQUIATRIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Dinamarca

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