Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance.

Yang, Zhentao; Wang, Yan; Liu, Sixue; Deng, Weixian; Lomeli, Shirley H; Moriceau, Gatien; Wohlschlegel, James; Piva, Marco; Lo, Roger S

Yang, Zhentao; Wang, Yan; Liu, Sixue; Deng, Weixian; Lomeli, Shirley H; Moriceau, Gatien; Wohlschlegel, James; Piva, Marco; Lo, Roger S.

Afiliação

Yang Z; Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Wang Y; Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Liu S; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Deng W; Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Lomeli SH; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Moriceau G; Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Wohlschlegel J; Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Piva M; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Lo RS; Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.

Cancer Discov ; 12(8): 1942-1959, 2022 08 05.

Article em En | MEDLINE | ID: mdl-35638972

Assuntos

Antígeno B7-H1; Melanoma; Proteínas Quinases Ativadas por Mitógeno; Proteínas Repressoras; Ubiquitina-Proteína Ligases; Animais; Linfócitos T CD8-Positivos; Linhagem Celular Tumoral; Resistencia a Medicamentos Antineoplásicos/genética; Humanos; Melanoma/genética; Camundongos; Proteínas Quinases Ativadas por Mitógeno/antagonistas & inibidores; Proteínas Repressoras/genética; Ubiquitina-Proteína Ligases/genética

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Proteínas Quinases Ativadas por Mitógeno / Ubiquitina-Proteína Ligases / Antígeno B7-H1 / Melanoma Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cancer Discov Ano de publicação: 2022 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google