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Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease.
Wong, Charis; Dakin, Rachel S; Williamson, Jill; Newton, Judith; Steven, Michelle; Colville, Shuna; Stavrou, Maria; Gregory, Jenna M; Elliott, Elizabeth; Mehta, Arpan R; Chataway, Jeremy; Swingler, Robert J; Parker, Richard Anthony; Weir, Christopher J; Stallard, Nigel; Parmar, Mahesh K B; Macleod, Malcolm R; Pal, Suvankar; Chandran, Siddharthan.
Afiliação
  • Wong C; Centre of Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
  • Dakin RS; Euan MacDonald Centre for Motor Neuron Disease Research, University of Edinburgh, Edinburgh, UK.
  • Williamson J; Anne Rowling Regenerative Neurology Clinic, University of Edinburgh, Edinburgh, UK.
  • Newton J; Centre of Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
  • Steven M; Euan MacDonald Centre for Motor Neuron Disease Research, University of Edinburgh, Edinburgh, UK.
  • Colville S; Anne Rowling Regenerative Neurology Clinic, University of Edinburgh, Edinburgh, UK.
  • Stavrou M; Centre of Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
  • Gregory JM; Euan MacDonald Centre for Motor Neuron Disease Research, University of Edinburgh, Edinburgh, UK.
  • Elliott E; Anne Rowling Regenerative Neurology Clinic, University of Edinburgh, Edinburgh, UK.
  • Mehta AR; Centre of Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
  • Chataway J; Euan MacDonald Centre for Motor Neuron Disease Research, University of Edinburgh, Edinburgh, UK.
  • Swingler RJ; Anne Rowling Regenerative Neurology Clinic, University of Edinburgh, Edinburgh, UK.
  • Parker RA; Edinburgh Clinical Trials Unit, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.
  • Weir CJ; Centre of Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
  • Stallard N; Euan MacDonald Centre for Motor Neuron Disease Research, University of Edinburgh, Edinburgh, UK.
  • Parmar MKB; Anne Rowling Regenerative Neurology Clinic, University of Edinburgh, Edinburgh, UK.
  • Macleod MR; Centre of Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
  • Pal S; Euan MacDonald Centre for Motor Neuron Disease Research, University of Edinburgh, Edinburgh, UK.
  • Chandran S; Anne Rowling Regenerative Neurology Clinic, University of Edinburgh, Edinburgh, UK.
BMJ Open ; 12(7): e064173, 2022 07 07.
Article em En | MEDLINE | ID: mdl-35798516
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trazodona / Doença dos Neurônios Motores / Doenças Neurodegenerativas / Esclerose Lateral Amiotrófica Tipo de estudo: Clinical_trials / Guideline / Prognostic_studies Limite: Humans Idioma: En Revista: BMJ Open Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trazodona / Doença dos Neurônios Motores / Doenças Neurodegenerativas / Esclerose Lateral Amiotrófica Tipo de estudo: Clinical_trials / Guideline / Prognostic_studies Limite: Humans Idioma: En Revista: BMJ Open Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido