The hypoxia-dependent angiogenic process in dental pulp.
J Oral Biosci
; 64(4): 381-391, 2022 12.
Article
em En
| MEDLINE
| ID: mdl-35998752
ABSTRACT
BACKGROUND:
In this review, we analyzed the existing literature to elucidate how the hypoxia-dependent angiogenic processes work in dental pulp. Angiogenesis is an essential biological process in the maturation and homeostasis of teeth. It involves multiple sequential steps such as endothelial cell proliferation and migration, cell-to-cell contact, and tube formation. HIGHLIGHT Clinical implications of understanding the process of angiogenesis include how the mineralization processes of dental pulp occur and how dental pulp maintains its homeostasis, preventing irreversible inflammation or necrosis.CONCLUSION:
The angiogenesis process in dental pulp regulates adequate concentrations of oxygen required for mineralization in root development and defense mechanisms against chronic stimuli.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Calcinose
/
Polpa Dentária
Limite:
Humans
Idioma:
En
Revista:
J Oral Biosci
Ano de publicação:
2022
Tipo de documento:
Article