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Novel allosteric glutaminase 1 inhibitors with macrocyclic structure activity relationship analysis.
Lee, Eun Ji; Duggirala, Krishna Babu; Lee, Yujin; Yun, Mi Ran; Jang, Jiyoon; Cyriac, Rajath; Jung, Myoung Eun; Choi, Gildon; Chae, Chong Hak; Cho, Byoung Chul; Lee, Kwangho.
Afiliação
  • Lee EJ; Department of Research Support, Yonsei Biomedical Science Institute, Yonsei University College of Medicine, Seoul 03722, South Korea.
  • Duggirala KB; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon 34114, South Korea; Medicinal Chemistry & Pharmacology, University of Science & Technology, Daejeon 34113, South Korea.
  • Lee Y; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon 34114, South Korea; Medicinal Chemistry & Pharmacology, University of Science & Technology, Daejeon 34113, South Korea.
  • Yun MR; Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul 03722, South Korea; Yonsei New Ii Han Institute for Integrative Lung Cancer Research, Yonsei University College of Medicine, Seoul 03722, South Korea.
  • Jang J; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon 34114, South Korea; Department of Chemistry, Sungkyunkwan University, Suwon 16419, South Korea.
  • Cyriac R; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon 34114, South Korea; Medicinal Chemistry & Pharmacology, University of Science & Technology, Daejeon 34113, South Korea.
  • Jung ME; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon 34114, South Korea.
  • Choi G; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon 34114, South Korea; Medicinal Chemistry & Pharmacology, University of Science & Technology, Daejeon 34113, South Korea.
  • Chae CH; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon 34114, South Korea.
  • Cho BC; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul 03722, South Korea. Electronic address: CBC1971@yuhs.ac.
  • Lee K; Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon 34114, South Korea; Medicinal Chemistry & Pharmacology, University of Science & Technology, Daejeon 34113, South Korea. Electronic address: kwangho@krict.re.kr.
Bioorg Med Chem Lett ; 75: 128956, 2022 11 01.
Article em En | MEDLINE | ID: mdl-36038117
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiadiazóis / Glutaminase Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Coréia do Sul
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiadiazóis / Glutaminase Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Coréia do Sul