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Efficacy and safety of switching from intravenous to oral antibiotics (amoxicillin-clavulanic acid) versus a full course of intravenous antibiotics in neonates with probable bacterial infection (RAIN): a multicentre, randomised, open-label, non-inferiority trial.
Keij, Fleur M; Kornelisse, René F; Hartwig, Nico G; van der Sluijs-Bens, Jacqueline; van Beek, Ron H T; van Driel, Arianne; van Rooij, Linda G M; van Dalen-Vink, Ilka; Driessen, Gertjan J A; Kenter, Sandra; von Lindern, Jeannette S; Eijkemans, Marianne; Stam-Stigter, Gerda M; Qi, Hongchao; van den Berg, Maartje M; Baartmans, Martin G A; van der Meer-Kappelle, Laura H; Meijssen, Clemens B; Norbruis, Obbe F; Heidema, Jojanneke; van Rossem, Maaike C; den Butter, Paul C P; Allegaert, Karel; Reiss, Irwin K M; Tramper-Stranders, Gerdien A.
Afiliação
  • Keij FM; Department of Paediatrics, Division of Neonatology, Erasmus University Medical Centre-Sophia Children's Hospital, Rotterdam, Netherlands; Department of Paediatrics, Franciscus Gasthuis & Vlietland, Rotterdam, Netherlands. Electronic address: f.keij@erasmusmc.nl.
  • Kornelisse RF; Department of Paediatrics, Division of Neonatology, Erasmus University Medical Centre-Sophia Children's Hospital, Rotterdam, Netherlands.
  • Hartwig NG; Department of Paediatrics, Franciscus Gasthuis & Vlietland, Rotterdam, Netherlands.
  • van der Sluijs-Bens J; Department of Paediatrics, Division of Neonatology, Maxima Medical Centre, Veldhoven, Netherlands.
  • van Beek RHT; Department of Paediatrics, Amphia Hospital, Breda, Netherlands.
  • van Driel A; Department of Paediatrics, IJsselland Hospital, Capelle aan den IJssel, Netherlands.
  • van Rooij LGM; Department of Paediatrics, Medisch Spectrum Twente, Enschede, Netherlands.
  • van Dalen-Vink I; Department of Paediatrics, Franciscus Gasthuis & Vlietland, Rotterdam, Netherlands.
  • Driessen GJA; Department of Paediatrics, Juliana Children's Hospital, Haga Teaching Hospital, the Hague, Netherlands.
  • Kenter S; Department of Paediatrics, Franciscus Gasthuis & Vlietland, Rotterdam, Netherlands.
  • von Lindern JS; Department of Paediatrics, Groene Hart Hospital, Gouda, Netherlands.
  • Eijkemans M; Department of Paediatrics, Catharina Hospital, Eindhoven, Netherlands.
  • Stam-Stigter GM; Department of Paediatrics, St Antonius Hospital, Nieuwegein, Netherlands.
  • Qi H; Department of Biostatistics, Erasmus University Medical Centre, Rotterdam, Netherlands.
  • van den Berg MM; Department of Paediatrics, Haaglanden Medical Centre, the Hague, Netherlands.
  • Baartmans MGA; Department of Paediatrics, Maasstad Hospital, Rotterdam, Netherlands.
  • van der Meer-Kappelle LH; Department of Paediatrics, Reinier de Graaf Hospital, Delft, Netherlands.
  • Meijssen CB; Department of Paediatrics, Meander Medical Centre, Amersfoort, Netherlands.
  • Norbruis OF; Department of Paediatrics, Isala Hospital, Zwolle, Netherlands.
  • Heidema J; Department of Paediatrics, St Antonius Hospital, Nieuwegein, Netherlands.
  • van Rossem MC; Department of Paediatrics, Rijnstate Hospital, Arnhem, Netherlands.
  • den Butter PCP; Department of Paediatrics, Ikazia Hospital, Rotterdam, Netherlands.
  • Allegaert K; Department of Hospital Pharmacy, Erasmus University Medical Centre, Rotterdam, Netherlands; Department of Development and Regeneration and Department of Pharmaceutical and Pharmacological Sciences, Catholic University of Leuven, Leuven, Belgium.
  • Reiss IKM; Department of Paediatrics, Division of Neonatology, Erasmus University Medical Centre-Sophia Children's Hospital, Rotterdam, Netherlands.
  • Tramper-Stranders GA; Department of Paediatrics, Division of Neonatology, Erasmus University Medical Centre-Sophia Children's Hospital, Rotterdam, Netherlands; Department of Paediatrics, Franciscus Gasthuis & Vlietland, Rotterdam, Netherlands. Electronic address: g.tramper@franciscus.nl.
Lancet Child Adolesc Health ; 6(11): 799-809, 2022 11.
Article em En | MEDLINE | ID: mdl-36088952
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Bacterianas / Combinação Amoxicilina e Clavulanato de Potássio Tipo de estudo: Clinical_trials / Guideline Limite: Adolescent / Adult / Child / Child, preschool / Humans / Infant / Newborn Idioma: En Revista: Lancet Child Adolesc Health Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Bacterianas / Combinação Amoxicilina e Clavulanato de Potássio Tipo de estudo: Clinical_trials / Guideline Limite: Adolescent / Adult / Child / Child, preschool / Humans / Infant / Newborn Idioma: En Revista: Lancet Child Adolesc Health Ano de publicação: 2022 Tipo de documento: Article