Performance Evaluation of Host Biomarker Combinations for the Diagnosis of Serious Bacterial Infection in Young Febrile Children: A Double-Blind, Multicentre, Observational Study.

Portefaix, Aurélie; Pons, Sylvie; Ouziel, Antoine; Basmaci, Romain; Rebaud, Philippe; Delafay, Marie-Caroline; Generenaz, Laurence; Oriol, Guy; Meunier, Boris; Abbas-Chorfa, Fatima; Trouillet-Assant, Sophie; Ginhoux, Tiphanie; Subtil, Fabien; Gillet, Yves; Brengel-Pesce, Karen; Javouhey, Etienne

Portefaix, Aurélie; Pons, Sylvie; Ouziel, Antoine; Basmaci, Romain; Rebaud, Philippe; Delafay, Marie-Caroline; Generenaz, Laurence; Oriol, Guy; Meunier, Boris; Abbas-Chorfa, Fatima; Trouillet-Assant, Sophie; Ginhoux, Tiphanie; Subtil, Fabien; Gillet, Yves; Brengel-Pesce, Karen; Javouhey, Etienne.

Afiliação

Portefaix A; Clinical Investigation Center (CIC 1407), Hospices Civils de Lyon, 69677 Bron, France.
Pons S; Laboratoire de Biométrie et Biologie Evolutive, CNRS, UMR 5558, Claude Bernard University of Lyon, 69622 Villeurbanne, France.
Ouziel A; Joint Research Unit Hospices Civils de Lyon-bioMérieux, Hôpital Lyon Sud, 69795 Pierre-Bénite, France.
Basmaci R; Joint Research Unit HCL-bioMérieux, EA 7426 "Pathophysiology of Injury-Induced Immunosuppression", Hospices Civils de Lyon-bioMérieux, Université Claude Bernard Lyon 1, 69003 Lyon, France.
Rebaud P; Pediatric Emergency and Intensive Care Unit, Hôpital Femme Mère Enfant, Hospices Civils of Lyon, 69677 Bron, France.
Delafay MC; Service de Pédiatrie-Urgences, Hôpital Louis-Mourier-Assistance Publique Hôpitaux de Paris (APHP), 92700 Colombes, France.
Generenaz L; Infections Antimicrobials Modelling Evolution (IAME), INSERM, UMR1137, Université de Paris, 75006 Paris, France.
Oriol G; Service de Pédiatrie-Néonatologie, Hôpital Nord-Ouest, Plateau d'Ouilly Gleizé BP 436, 69655 Villefranche-sur-Saône, France.
Meunier B; Service de Pédiatrie-Néonatologie, Hôpital Nord-Ouest, Plateau d'Ouilly Gleizé BP 436, 69655 Villefranche-sur-Saône, France.
Abbas-Chorfa F; Joint Research Unit Hospices Civils de Lyon-bioMérieux, Hôpital Lyon Sud, 69795 Pierre-Bénite, France.
Trouillet-Assant S; Joint Research Unit HCL-bioMérieux, EA 7426 "Pathophysiology of Injury-Induced Immunosuppression", Hospices Civils de Lyon-bioMérieux, Université Claude Bernard Lyon 1, 69003 Lyon, France.
Ginhoux T; Joint Research Unit Hospices Civils de Lyon-bioMérieux, Hôpital Lyon Sud, 69795 Pierre-Bénite, France.
Subtil F; Joint Research Unit HCL-bioMérieux, EA 7426 "Pathophysiology of Injury-Induced Immunosuppression", Hospices Civils de Lyon-bioMérieux, Université Claude Bernard Lyon 1, 69003 Lyon, France.
Gillet Y; Joint Research Unit Hospices Civils de Lyon-bioMérieux, Hôpital Lyon Sud, 69795 Pierre-Bénite, France.
Brengel-Pesce K; Joint Research Unit HCL-bioMérieux, EA 7426 "Pathophysiology of Injury-Induced Immunosuppression", Hospices Civils de Lyon-bioMérieux, Université Claude Bernard Lyon 1, 69003 Lyon, France.
Javouhey E; Laboratoire de Biométrie et Biologie Evolutive, CNRS, UMR 5558, Claude Bernard University of Lyon, 69622 Villeurbanne, France.

J Clin Med ; 11(21)2022 Nov 04.

Article em En | MEDLINE | ID: mdl-36362791

Palavras-chave

C-reactive protein (CRP); IFN-Î³-induced protein 10 (IP-10); bacterial- and viral-induced host biomarkers; interleukin 6 (IL-6); machine learning; myxovirus resistance protein 1 (MxA); neutrophil gelatinase-associated lipocalin-2 (NGAL); paediatric serious bacterial infection; procalcitonin (PCT); tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials / Diagnostic_studies / Observational_studies / Prognostic_studies Idioma: En Revista: J Clin Med Ano de publicação: 2022 Tipo de documento: Article País de afiliação: França

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google