Characterization of protein isoform diversity in human umbilical vein endothelial cells via long-read proteogenomics.

Mehlferber, Madison M; Jeffery, Erin D; Saquing, Jamie; Jordan, Ben T; Sheynkman, Leon; Murali, Mayank; Genet, Gael; Acharya, Bipul R; Hirschi, Karen K; Sheynkman, Gloria M

Mehlferber, Madison M; Jeffery, Erin D; Saquing, Jamie; Jordan, Ben T; Sheynkman, Leon; Murali, Mayank; Genet, Gael; Acharya, Bipul R; Hirschi, Karen K; Sheynkman, Gloria M.

Afiliação

Mehlferber MM; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA, USA.
Jeffery ED; Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, Virginia, USA.
Saquing J; Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, Virginia, USA.
Jordan BT; Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, Virginia, USA.
Sheynkman L; Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, Virginia, USA.
Murali M; Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, Virginia, USA.
Genet G; Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, Virginia, USA.
Acharya BR; Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA, USA.
Hirschi KK; Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA, USA.
Sheynkman GM; Cardiovascular Research Center, University of Virginia, Charlottesville, VA, USA.

RNA Biol ; 19(1): 1228-1243, 2022 01.

Article em En | MEDLINE | ID: mdl-36457147

Assuntos

Proteogenômica; Humanos; Células Endoteliais da Veia Umbilical Humana; Isoformas de Proteínas/genética; Processamento Alternativo; RNA

Palavras-chave

HUVECs; Long-read RNA-seq; MetaMorpheus; Orbitrap; PacBio; alternative splicing; cardiovascular; endothelial cells; isoforms; mass-spectrometry-based proteomics; nextflow; protein isoforms; proteogenomics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteogenômica Limite: Humans Idioma: En Revista: RNA Biol Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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