Dexmedetomidine Increases MMP-12 and MBP Concentrations after Coronary Artery Bypass Graft Surgery with Extracorporeal Circulation Anaesthesia without Impacting Cognitive Function: A Randomised Control Trial.

Kowalczyk, Michal; Panasiuk-Kowalczyk, Anna; Stadnik, Adam; Guz, Malgorzata; Cybulski, Marek; Jeleniewicz, Witold; Stepulak, Andrzej; Kwiatosz-Muc, Magdalena

Kowalczyk, Michal; Panasiuk-Kowalczyk, Anna; Stadnik, Adam; Guz, Malgorzata; Cybulski, Marek; Jeleniewicz, Witold; Stepulak, Andrzej; Kwiatosz-Muc, Magdalena.

Afiliação

Kowalczyk M; 1st Department of Anaesthesiology and Intensive Care, Medical University of Lublin, ul. Jaczewskiego 8, 20-954 Lublin, Poland.
Panasiuk-Kowalczyk A; 1st Department of Anaesthesiology and Intensive Care, Medical University of Lublin, ul. Jaczewskiego 8, 20-954 Lublin, Poland.
Stadnik A; Department of Cardiac Surgery, Medical University of Lublin, ul. Jaczewskiego 8, 20-954 Lublin, Poland.
Guz M; Department of Biochemistry and Molecular Biology, Medical University of Lublin, ul. Chodzki 1, 20-093 Lublin, Poland.
Cybulski M; Department of Biochemistry and Molecular Biology, Medical University of Lublin, ul. Chodzki 1, 20-093 Lublin, Poland.
Jeleniewicz W; Department of Biochemistry and Molecular Biology, Medical University of Lublin, ul. Chodzki 1, 20-093 Lublin, Poland.
Stepulak A; Department of Biochemistry and Molecular Biology, Medical University of Lublin, ul. Chodzki 1, 20-093 Lublin, Poland.
Kwiatosz-Muc M; 1st Department of Anaesthesiology and Intensive Care, Medical University of Lublin, ul. Jaczewskiego 8, 20-954 Lublin, Poland.

Int J Environ Res Public Health ; 19(24)2022 12 08.

Article em En | MEDLINE | ID: mdl-36554397

Assuntos

Anestesia; Dexmedetomidina; Humanos; Dexmedetomidina/uso terapêutico; Dexmedetomidina/farmacologia; Metaloproteinase 12 da Matriz/farmacologia; Proteína Básica da Mielina/farmacologia; Ponte de Artéria Coronária; Cognição; Circulação Extracorpórea

Palavras-chave

anaesthesia; coronary artery bypass graft surgery; dexmedetomidine; extracorporeal circulation; matrix metalloproteinase-12; myelin basic protein

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dexmedetomidina / Anestesia Tipo de estudo: Clinical_trials / Observational_studies Limite: Humans Idioma: En Revista: Int J Environ Res Public Health Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Polônia

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