Neurosteroids and translocator protein 18 kDa (TSPO) in depression: implications for synaptic plasticity, cognition, and treatment options.

Rupprecht, Rainer; Pradhan, Arpit Kumar; Kufner, Marco; Brunner, Lisa Marie; Nothdurfter, Caroline; Wein, Simon; Schwarzbach, Jens; Puig, Xenia; Rupprecht, Christian; Rammes, Gerhard

Neurosteroids and translocator protein 18 kDa (TSPO) in depression: implications for synaptic plasticity, cognition, and treatment options.

Rupprecht, Rainer; Pradhan, Arpit Kumar; Kufner, Marco; Brunner, Lisa Marie; Nothdurfter, Caroline; Wein, Simon; Schwarzbach, Jens; Puig, Xenia; Rupprecht, Christian; Rammes, Gerhard.

Afiliação

Rupprecht R; Department of Psychiatry and Psychotherapy, University Regensburg, Universitätsstrasse 84, 93053, Regensburg, Germany. Rainer.Rupprecht@medbo.de.
Pradhan AK; Experimental Neuropharmacology, Department of Anesthesiology, Technical University Munich, Munich, Germany.
Kufner M; Department of Psychiatry and Psychotherapy, University Regensburg, Universitätsstrasse 84, 93053, Regensburg, Germany.
Brunner LM; Department of Psychiatry and Psychotherapy, University Regensburg, Universitätsstrasse 84, 93053, Regensburg, Germany.
Nothdurfter C; Department of Psychiatry and Psychotherapy, University Regensburg, Universitätsstrasse 84, 93053, Regensburg, Germany.
Wein S; Department of Psychiatry and Psychotherapy, University Regensburg, Universitätsstrasse 84, 93053, Regensburg, Germany.
Schwarzbach J; Department of Psychiatry and Psychotherapy, University Regensburg, Universitätsstrasse 84, 93053, Regensburg, Germany.
Puig X; Experimental Neuropharmacology, Department of Anesthesiology, Technical University Munich, Munich, Germany.
Rupprecht C; Experimental Neuropharmacology, Department of Anesthesiology, Technical University Munich, Munich, Germany.
Rammes G; Experimental Neuropharmacology, Department of Anesthesiology, Technical University Munich, Munich, Germany.

Eur Arch Psychiatry Clin Neurosci ; 273(7): 1477-1487, 2023 Oct.

Article em En | MEDLINE | ID: mdl-36574032

Assuntos

Ansiolíticos; Depressão Pós-Parto; Transtorno Depressivo Maior; Neuroesteroides; Humanos; Feminino; Neuroesteroides/farmacologia; Ansiolíticos/uso terapêutico; Pregnanolona/farmacologia; Ligantes; Depressão; Depressão Pós-Parto/tratamento farmacológico; Transtorno Depressivo Maior/tratamento farmacológico; Neurotransmissores/farmacologia; Neurotransmissores/metabolismo; Receptores de GABA-A; Benzodiazepinas; Proteínas de Transporte; Plasticidade Neuronal; Cognição; Ácido gama-Aminobutírico; Receptores de GABA/metabolismo

Palavras-chave

Depression; Inflammation; Neurosteroids; TSPO; Treatment

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ansiolíticos / Depressão Pós-Parto / Transtorno Depressivo Maior / Neuroesteroides Limite: Female / Humans Idioma: En Revista: Eur Arch Psychiatry Clin Neurosci Assunto da revista: NEUROLOGIA / PSIQUIATRIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha

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