Incidence of Retinal Detachment, Macular Edema, and Ocular Hypertension after Neodymium:Yttrium-Aluminum-Garnet Capsulotomy: A Population-Based Nationwide Study-The French YAG 2 Study.
Ophthalmology
; 130(5): 478-487, 2023 05.
Article
em En
| MEDLINE
| ID: mdl-36581227
ABSTRACT
PURPOSE:
To estimate the incidence and assess the risk factors associated with 3 adverse events (AEs) after neodymiumyttrium-aluminum-garnet posterior capsulotomy (NdYAG-caps) ocular hypertension (OHT), macular edema (ME), and retinal detachment (RD).DESIGN:
Observational cohort study using a nationwide claims database.PARTICIPANTS:
Adults who underwent NdYAG-caps between 2014 and 2017, with no ocular disease history in the year before.METHODS:
Patients who underwent NdYAG-caps were identified using data from the French national representative sample and followed up for 12 months postprocedure. The time to AE was assessed using the Kaplan-Meier method. Factors associated with AE were assessed using Cox models. MAIN OUTCOMEMEASURES:
NeodymiumYAG-caps epidemiology, patients' characteristics, proportion of patients with AE, and hazard ratios (HRs) associated with variables identified as factors associated with AEs.RESULTS:
During the study period, 6210 patients received NdYAG-caps (7958 procedures). The mean age (± standard deviation) at NdYAG-caps was 75.0 (± 10.3) years. The 3-month and 12-month overall AE rates (≥ 1 AE of interest) were 8.6% and 13.3%, respectively. Among patients with ≥ 1 AE of interest, 68.4% of AEs occurred within 3 months post-NdYAG-caps. Three-month rates were ≈5% for OHT and ME. Retinal detachment remained ≤ 0.5% over follow-up. Cox models showed that patients with NdYAG-caps performed within 1 year after cataract surgery had a higher risk of AEs than those with later NdYAG-caps (hazard ratio [HR], 1.314 [1.034-1.669], P = 0.0256), notably ME (HR, 1.500 [1.087-2.070], P = 0.0137). Diabetic patients were more at risk of OHT (HR, 1.233 [1.005-1.513], P = 0.0448) and ME (HR, 1.810 [1.446-2.266], P < 0.0001) than nondiabetic patients. Patients with NdYAG-caps performed between 1 and 2 years after cataract surgery were more at risk of OHT than patients with later NdYAG-caps (HR, 1.429 [1.185-1.723], P = 0.0002).CONCLUSIONS:
According to a national claims database, OHT and ME were the most frequent AEs of interest post-NdYAG-caps, mainly observed within 3 months postprocedure, highlighting the need for a close follow-up during this period or a delayed capsulotomy. Diabetes and an early NdYAG-caps after cataract surgery were among the main drivers for AE occurrence. FINANCIAL DISCLOSURE(S) Proprietary or commercial disclosure may be found after the references.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Descolamento Retiniano
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Extração de Catarata
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Edema Macular
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Hipertensão Ocular
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Terapia a Laser
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Opacificação da Cápsula
/
Cápsula do Cristalino
Tipo de estudo:
Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Aged
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Aged80
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Humans
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Middle aged
Idioma:
En
Revista:
Ophthalmology
Ano de publicação:
2023
Tipo de documento:
Article