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An atlas of substrate specificities for the human serine/threonine kinome.
Johnson, Jared L; Yaron, Tomer M; Huntsman, Emily M; Kerelsky, Alexander; Song, Junho; Regev, Amit; Lin, Ting-Yu; Liberatore, Katarina; Cizin, Daniel M; Cohen, Benjamin M; Vasan, Neil; Ma, Yilun; Krismer, Konstantin; Robles, Jaylissa Torres; van de Kooij, Bert; van Vlimmeren, Anne E; Andrée-Busch, Nicole; Käufer, Norbert F; Dorovkov, Maxim V; Ryazanov, Alexey G; Takagi, Yuichiro; Kastenhuber, Edward R; Goncalves, Marcus D; Hopkins, Benjamin D; Elemento, Olivier; Taatjes, Dylan J; Maucuer, Alexandre; Yamashita, Akio; Degterev, Alexei; Uduman, Mohamed; Lu, Jingyi; Landry, Sean D; Zhang, Bin; Cossentino, Ian; Linding, Rune; Blenis, John; Hornbeck, Peter V; Turk, Benjamin E; Yaffe, Michael B; Cantley, Lewis C.
Afiliação
  • Johnson JL; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Yaron TM; Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
  • Huntsman EM; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Kerelsky A; Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
  • Song J; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.
  • Regev A; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.
  • Lin TY; Tri-Institutional PhD Program in Computational Biology & Medicine, Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center and The Rockefeller University, New York, NY, USA.
  • Liberatore K; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Cizin DM; Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
  • Cohen BM; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Vasan N; Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
  • Ma Y; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.
  • Krismer K; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Robles JT; Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
  • van de Kooij B; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • van Vlimmeren AE; Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
  • Andrée-Busch N; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Käufer NF; Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
  • Dorovkov MV; Weill Cornell Graduate School of Medical Sciences, Cell and Developmental Biology Program, New York, NY, USA.
  • Ryazanov AG; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Takagi Y; Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
  • Kastenhuber ER; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Goncalves MD; Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
  • Hopkins BD; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Elemento O; Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
  • Taatjes DJ; Department of Medicine, Division of Hematology/Oncology, Columbia University Irving Medical Center, New York, NY, USA.
  • Maucuer A; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY, USA.
  • Yamashita A; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Degterev A; Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
  • Uduman M; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Lu J; Center for Precision Cancer Medicine, Koch Institute for Integrative Cancer Biology, Departments of Biology and Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Landry SD; Department of Pharmacology, Yale School of Medicine, New Haven, CT, USA.
  • Zhang B; Department of Chemistry, Yale University, New Haven, CT, USA.
  • Cossentino I; Center for Precision Cancer Medicine, Koch Institute for Integrative Cancer Biology, Departments of Biology and Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Linding R; Center for Precision Cancer Medicine, Koch Institute for Integrative Cancer Biology, Departments of Biology and Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Blenis J; Institute of Genetics, Technische Universität Braunschweig, Braunschweig, Germany.
  • Hornbeck PV; Institute of Genetics, Technische Universität Braunschweig, Braunschweig, Germany.
  • Turk BE; Department of Pharmacology, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ, USA.
  • Yaffe MB; Department of Pharmacology, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ, USA.
  • Cantley LC; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA.
Nature ; 613(7945): 759-766, 2023 01.
Article em En | MEDLINE | ID: mdl-36631611

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Serina / Treonina / Proteínas Serina-Treonina Quinases / Proteoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nature Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Serina / Treonina / Proteínas Serina-Treonina Quinases / Proteoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nature Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos