SON-light activation of glucose regulation.

Geoghegan, Gisela; Simcox, Judith

Geoghegan, Gisela; Simcox, Judith.

Afiliação

Geoghegan G; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.
Simcox J; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA. Electronic address: jsimcox@wisc.edu.

Cell ; 186(2): 238-240, 2023 01 19.

Article em En | MEDLINE | ID: mdl-36669471

ABSTRACT

ABSTRACT

Body temperature maintenance is an important regulator of glucose homeostasis. In this issue of Cell, Meng et al. discover a regulatory axis in which light activation of photoreceptive retinal ganglia stimulates the supraoptic nucleus (SON) to inhibit brown adipose tissue (BAT) thermogenesis and impair glucose homeostasis. This could explain the impact of constant light exposure on metabolism.

Assuntos

Glucose; Núcleo Supraóptico; Glucose/metabolismo; Núcleo Supraóptico/metabolismo; Termogênese/fisiologia; Homeostase; Tecido Adiposo Marrom/metabolismo; Metabolismo Energético

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Núcleo Supraóptico / Glucose Idioma: En Revista: Cell Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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