Etoposide promotes DNA loop trapping and barrier formation by topoisomerase II.

Le, Tung T; Wu, Meiling; Lee, Joyce H; Bhatt, Neti; Inman, James T; Berger, James M; Wang, Michelle D

Le, Tung T; Wu, Meiling; Lee, Joyce H; Bhatt, Neti; Inman, James T; Berger, James M; Wang, Michelle D.

Afiliação

Le TT; Howard Hughes Medical Institute, Cornell University, Ithaca, NY, USA.
Wu M; Department of Physics and LASSP, Cornell University, Ithaca, NY, USA.
Lee JH; Howard Hughes Medical Institute, Cornell University, Ithaca, NY, USA.
Bhatt N; Department of Physics and LASSP, Cornell University, Ithaca, NY, USA.
Inman JT; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Berger JM; Department of Physics and LASSP, Cornell University, Ithaca, NY, USA.
Wang MD; Howard Hughes Medical Institute, Cornell University, Ithaca, NY, USA.

Nat Chem Biol ; 19(5): 641-650, 2023 05.

Article em En | MEDLINE | ID: mdl-36717711

Assuntos

DNA Topoisomerases Tipo II; Inibidores da Topoisomerase II; Humanos; Etoposídeo/farmacologia; Inibidores da Topoisomerase II/farmacologia; DNA Topoisomerases Tipo II/genética; DNA

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA Topoisomerases Tipo II / Inibidores da Topoisomerase II Limite: Humans Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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