Integrated Nanorod-Mediated PD-L1 Downregulation in Combination with Oxidative-Stress Immunogene Therapy against Cancer.

Wu, Shuaiying; Zhang, Jianzhong; Pan, Jie; Bai, Shuang; Wang, Ziying; Chen, Yulun; Xu, Dazhuang; An, Yibo; Liu, Chao; Chu, Chengchao; Dai, Qixuan; Jiang, Lai; Lu, Zhixiang; Liu, Gang

Wu, Shuaiying; Zhang, Jianzhong; Pan, Jie; Bai, Shuang; Wang, Ziying; Chen, Yulun; Xu, Dazhuang; An, Yibo; Liu, Chao; Chu, Chengchao; Dai, Qixuan; Jiang, Lai; Lu, Zhixiang; Liu, Gang.

Afiliação

Wu S; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
Zhang J; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
Pan J; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
Bai S; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
Wang Z; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Biology, School of Life Sciences, Xiamen University, Xiamen, 361102, China.
Chen Y; School of Medicine, Xiamen University, Xiamen, 361102, China.
Xu D; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
An Y; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
Liu C; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
Chu C; School of Medicine, Xiamen University, Xiamen, 361102, China.
Dai Q; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
Jiang L; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
Lu Z; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
Liu G; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.

Adv Healthc Mater ; 12(17): e2300110, 2023 07.

Article em En | MEDLINE | ID: mdl-36773310

Assuntos

Imunoterapia; Neoplasias; Humanos; Regulação para Baixo; Neoplasias/terapia; Estresse Oxidativo; RNA Interferente Pequeno/genética; Antígeno B7-H1/genética; Linhagem Celular Tumoral; Microambiente Tumoral

Palavras-chave

PD-L1 blockade; immunogenic cell death (ICD); oxidative stress; sonodynamic therapy (SDT); tumor microenvironment (TME)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoterapia / Neoplasias Limite: Humans Idioma: En Revista: Adv Healthc Mater Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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