Non-canonical pattern recognition of a pathogen-derived metabolite by a nuclear hormone receptor identifies virulent bacteria in C. elegans.

Peterson, Nicholas D; Tse, Samantha Y; Huang, Qiuyu Judy; Wani, Khursheed A; Schiffer, Celia A; Pukkila-Worley, Read

Non-canonical pattern recognition of a pathogen-derived metabolite by a nuclear hormone receptor identifies virulent bacteria in C. elegans.

Peterson, Nicholas D; Tse, Samantha Y; Huang, Qiuyu Judy; Wani, Khursheed A; Schiffer, Celia A; Pukkila-Worley, Read.

Afiliação

Peterson ND; Program in Innate Immunity, Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Tse SY; Program in Innate Immunity, Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Huang QJ; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Wani KA; Program in Innate Immunity, Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Schiffer CA; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Pukkila-Worley R; Program in Innate Immunity, Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA. Electronic address: read.pukkila-worley@umassmed.edu.

Immunity ; 56(4): 768-782.e9, 2023 04 11.

Article em En | MEDLINE | ID: mdl-36804958

Assuntos

Proteínas de Caenorhabditis elegans; Caenorhabditis elegans; Animais; Proteínas de Caenorhabditis elegans/genética; Proteínas de Caenorhabditis elegans/metabolismo; Regulação da Expressão Gênica; Receptores Citoplasmáticos e Nucleares/metabolismo; Imunidade Inata; Bactérias; Pseudomonas aeruginosa/metabolismo

Palavras-chave

Caenorhabditis elegans; Pseudomonas aeruginosa; host-pathogen interactions; innate immunity; intestinal epithelial cells; nuclear hormone receptor; pathogen sensing; pattern recognition receptor; patterns of pathogenesis; phenazines

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Caenorhabditis elegans / Proteínas de Caenorhabditis elegans Limite: Animals Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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