Zika virus induced microcephaly and aberrant hematopoietic cell differentiation modeled in novel neonatal humanized mice.

Schmitt, Kimberly; Curlin, James Z; Remling-Mulder, Leila; Aboellail, Tawfik; Akkina, Ramesh

Schmitt, Kimberly; Curlin, James Z; Remling-Mulder, Leila; Aboellail, Tawfik; Akkina, Ramesh.

Afiliação

Schmitt K; Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO, United States.
Curlin JZ; Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO, United States.
Remling-Mulder L; Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO, United States.
Aboellail T; Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO, United States.
Akkina R; Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO, United States.

Front Immunol ; 14: 1060959, 2023.

Article em En | MEDLINE | ID: mdl-36825016

Assuntos

Microcefalia; Malformações do Sistema Nervoso; Infecção por Zika virus; Animais; Humanos; Camundongos; Diferenciação Celular; Microcefalia/virologia; Malformações do Sistema Nervoso/virologia; Zika virus; Infecção por Zika virus/complicações

Palavras-chave

A dual-purpose hu-mouse model for Zika; Modeling Zika pathologies in newborns; Neonatal hu-mouse model for Zika; Neuronal impairment by Zika in childhood; Zika viral effects on human CD34+ HSC; Zika virus and aberrant B cell development; Zika virus and hematopoiesis; humanized mouse model for Zika microcephaly

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecção por Zika virus / Microcefalia / Malformações do Sistema Nervoso Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Front Immunol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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