PBPK modeling to evaluate maximum tolerated doses: A case study with 3-chloroallyl alcohol.

Conolly, Rory P; Clewell, Harvey J; Moore, Martha M; Campbell, Jerry L; Cheng, Wanyun; Gentry, R Robinan

Conolly, Rory P; Clewell, Harvey J; Moore, Martha M; Campbell, Jerry L; Cheng, Wanyun; Gentry, R Robinan.

Afiliação

Conolly RP; Ramboll US Corporation, Monroe, LA, United States.
Clewell HJ; Ramboll US Corporation, Monroe, LA, United States.
Moore MM; Martha M. Moore LLC, Little Rock, AR, United States.
Campbell JL; Ramboll US Corporation, Monroe, LA, United States.
Cheng W; UPL Limited, Inc, Durham, NC, United States.
Gentry RR; Ramboll US Corporation, Monroe, LA, United States.

Front Pharmacol ; 14: 1088011, 2023.

Article em En | MEDLINE | ID: mdl-36909196

Palavras-chave

3-chloroallyl alcohol; MTD; PBPK; genotoxicity; reduction

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Qualitative_research Idioma: En Revista: Front Pharmacol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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