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Early Growth Response-1: Friend or Foe in the Heart?
Billah, Muntasir; Naz, Adiba; Noor, Rashed; Bhindi, Ravinay; Khachigian, Levon M.
Afiliação
  • Billah M; Department of Cardiology, Kolling Institute of Medical Research, Northern Sydney Local Health District, Sydney, NSW, Australia; Sydney Medical School Northern, The University of Sydney, Sydney, NSW, Australia. Electronic address: billah.muntasir08@gmail.com.
  • Naz A; Department of Molecular Sciences, Faculty of Science and Engineering, Macquarie University, Sydney, NSW, Australia.
  • Noor R; School of Environmental and Life Sciences, Independent University Bangladesh, Dhaka, Bangladesh.
  • Bhindi R; Department of Cardiology, Kolling Institute of Medical Research, Northern Sydney Local Health District, Sydney, NSW, Australia; Sydney Medical School Northern, The University of Sydney, Sydney, NSW, Australia.
  • Khachigian LM; Vascular Biology and Translational Research, School of Biomedical Sciences, University of New South Wales, Sydney, NSW, Australia.
Heart Lung Circ ; 32(5): e23-e35, 2023 May.
Article em En | MEDLINE | ID: mdl-37024319
ABSTRACT
Cardiovascular disease is a major cause of mortality and morbidity worldwide. Early growth response-1 (Egr-1) plays a critical regulatory role in a range of experimental models of cardiovascular diseases. Egr-1 is an immediate-early gene and is upregulated by various stimuli including shear stress, oxygen deprivation, oxidative stress and nutrient deprivation. However, recent research suggests a new, underexplored cardioprotective side of Egr-1. The main purpose of this review is to explore and summarise the dual nature of Egr-1 in cardiovascular pathobiology.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Heart Lung Circ Assunto da revista: ANGIOLOGIA / CARDIOLOGIA Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Heart Lung Circ Assunto da revista: ANGIOLOGIA / CARDIOLOGIA Ano de publicação: 2023 Tipo de documento: Article