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Catalytic Degraders Effectively Address Kinase Site Mutations in EML4-ALK Oncogenic Fusions.
Gao, Yang; Jiang, Baishan; Kim, Hellen; Berberich, Matthew J; Che, Jianwei; Donovan, Katherine A; Hatcher, John M; Huerta, Fidel; Kwiatkowski, Nicholas P; Liu, Yingpeng; Liuni, Peter P; Metivier, Rebecca J; Murali, Vineeth K; Nowak, Radoslaw P; Zhang, Tinghu; Fischer, Eric S; Gray, Nathanael S; Jones, Lyn H.
Afiliação
  • Gao Y; Center for Protein Degradation, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States.
  • Jiang B; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02215, United States.
  • Kim H; Center for Protein Degradation, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States.
  • Berberich MJ; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02215, United States.
  • Che J; Center for Protein Degradation, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States.
  • Donovan KA; Center for Protein Degradation, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States.
  • Hatcher JM; Center for Protein Degradation, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States.
  • Huerta F; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02215, United States.
  • Kwiatkowski NP; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02215, United States.
  • Liu Y; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States.
  • Liuni PP; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02215, United States.
  • Metivier RJ; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States.
  • Murali VK; Center for Protein Degradation, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States.
  • Nowak RP; Center for Protein Degradation, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States.
  • Zhang T; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02215, United States.
  • Fischer ES; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States.
  • Gray NS; Center for Protein Degradation, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States.
  • Jones LH; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02215, United States.
J Med Chem ; 66(8): 5524-5535, 2023 04 27.
Article em En | MEDLINE | ID: mdl-37036171
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pulmonares / Antineoplásicos Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pulmonares / Antineoplásicos Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos