The Anticancer Drug Daunomycin Directly Affects Gene Expression and DNA Structure.

Nishio, Takashi; Shimada, Yohji; Yoshikawa, Yuko; Kenmotsu, Takahiro; Schiessel, Helmut; Yoshikawa, Kenichi

Nishio, Takashi; Shimada, Yohji; Yoshikawa, Yuko; Kenmotsu, Takahiro; Schiessel, Helmut; Yoshikawa, Kenichi.

Afiliação

Nishio T; Faculty of Life and Medical Sciences, Doshisha University, Kyoto 610-0394, Japan.
Shimada Y; Cluster of Excellence Physics of Life, TU Dresden, 01307 Dresden, Germany.
Yoshikawa Y; Faculty of Life and Medical Sciences, Doshisha University, Kyoto 610-0394, Japan.
Kenmotsu T; Faculty of Life and Medical Sciences, Doshisha University, Kyoto 610-0394, Japan.
Schiessel H; Faculty of Life and Medical Sciences, Doshisha University, Kyoto 610-0394, Japan.
Yoshikawa K; Cluster of Excellence Physics of Life, TU Dresden, 01307 Dresden, Germany.

Int J Mol Sci ; 24(7)2023 Apr 01.

Article em En | MEDLINE | ID: mdl-37047603

Assuntos

DNA; Daunorrubicina; Daunorrubicina/farmacologia; DNA/química; Antibióticos Antineoplásicos/farmacologia; Espermina/farmacologia; Conformação de Ácido Nucleico; Expressão Gênica

Palavras-chave

anticancer drug; atomic force microscopy (AFM); cell-free in vitro luciferase assay; daunomycin; double-strand breaks (DSBs); gene expression; higher-order structure of DNA; polyamine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA / Daunorrubicina Idioma: En Revista: Int J Mol Sci Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão

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