A cochleate formulation optimized by D-optimal mixture design enhances oral bioavailability of Revaprazan.

Goo, Yoon Tae; Kim, Min Song; Choi, Ji Yeh; Sin, Gi Hyeong; Hong, Sun Ho; Kim, Chang Hyun; Choi, Young Wook

Goo, Yoon Tae; Kim, Min Song; Choi, Ji Yeh; Sin, Gi Hyeong; Hong, Sun Ho; Kim, Chang Hyun; Choi, Young Wook.

Afiliação

Goo YT; College of Pharmacy, Chung-Ang University, Seoul, Republic of Korea.
Kim MS; College of Pharmacy, Chung-Ang University, Seoul, Republic of Korea.
Choi JY; Department of Psychology, York University, Toronto, Canada.
Sin GH; College of Pharmacy, Chung-Ang University, Seoul, Republic of Korea.
Hong SH; College of Pharmacy, Chung-Ang University, Seoul, Republic of Korea.
Kim CH; College of Pharmacy, Chung-Ang University, Seoul, Republic of Korea.
Choi YW; College of Pharmacy, Chung-Ang University, Seoul, Republic of Korea.

J Liposome Res ; 34(1): 31-43, 2024 Mar.

Article em En | MEDLINE | ID: mdl-37158827

Assuntos

Dimiristoilfosfatidilcolina; Lipossomos; Pirimidinonas; Tetra-Hidroisoquinolinas; Ratos; Animais; Disponibilidade Biológica; Administração Oral; Tamanho da Partícula

Palavras-chave

D-optimal mixture design; Revaprazan; cochleate; enzyme stability; laurdan spectroscopy; oral bioavailability

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinonas / Tetra-Hidroisoquinolinas / Dimiristoilfosfatidilcolina / Lipossomos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Liposome Res Assunto da revista: BIOQUIMICA Ano de publicação: 2024 Tipo de documento: Article

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