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Genetically proxied glucose-lowering drug target perturbation and risk of cancer: a Mendelian randomisation analysis.
Yarmolinsky, James; Bouras, Emmanouil; Constantinescu, Andrei; Burrows, Kimberley; Bull, Caroline J; Vincent, Emma E; Martin, Richard M; Dimopoulou, Olympia; Lewis, Sarah J; Moreno, Victor; Vujkovic, Marijana; Chang, Kyong-Mi; Voight, Benjamin F; Tsao, Philip S; Gunter, Marc J; Hampe, Jochen; Pellatt, Andrew J; Pharoah, Paul D P; Schoen, Robert E; Gallinger, Steven; Jenkins, Mark A; Pai, Rish K; Gill, Dipender; Tsilidis, Kostas K.
Afiliação
  • Yarmolinsky J; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK. james.yarmolinsky@bristol.ac.uk.
  • Bouras E; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. james.yarmolinsky@bristol.ac.uk.
  • Constantinescu A; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece.
  • Burrows K; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • Bull CJ; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Vincent EE; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • Martin RM; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Dimopoulou O; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • Lewis SJ; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Moreno V; School of Translational Health Sciences, University of Bristol, Bristol, UK.
  • Vujkovic M; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • Chang KM; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Voight BF; School of Translational Health Sciences, University of Bristol, Bristol, UK.
  • Tsao PS; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • Gunter MJ; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Hampe J; NIHR Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol, Bristol, UK.
  • Pellatt AJ; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • Pharoah PDP; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Schoen RE; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • Gallinger S; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Jenkins MA; Biomarkers and Susceptibility Unit, Oncology Data Analytics Program, Catalan Institute of Oncology (ICO), L'Hospitalet de Llobregat, Barcelona, Spain.
  • Pai RK; Colorectal Cancer Group, ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.
  • Gill D; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.
  • Tsilidis KK; Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Diabetologia ; 66(8): 1481-1500, 2023 08.
Article em En | MEDLINE | ID: mdl-37171501
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Neoplasias da Mama / Neoplasias Colorretais / Diabetes Mellitus Tipo 2 Tipo de estudo: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans / Male Idioma: En Revista: Diabetologia Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Neoplasias da Mama / Neoplasias Colorretais / Diabetes Mellitus Tipo 2 Tipo de estudo: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans / Male Idioma: En Revista: Diabetologia Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido