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Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity.
Saito, Kenji; Sekiya, Motohiro; Kainoh, Kenta; Yoshino, Ryunosuke; Hayashi, Akio; Han, Song-Iee; Araki, Masaya; Ohno, Hiroshi; Takeuchi, Yoshinori; Tsuyuzaki, Tomomi; Yamazaki, Daichi; Wanpei, Chen; Hada, Lisa; Watanabe, Sho; Paramita Adi Putri, Putu Indah; Murayama, Yuki; Sugano, Yoko; Osaki, Yoshinori; Iwasaki, Hitoshi; Yahagi, Naoya; Suzuki, Hiroaki; Miyamoto, Takafumi; Matsuzaka, Takashi; Shimano, Hitoshi.
Afiliação
  • Saito K; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
  • Sekiya M; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan. Electronic address: msekiya@md.tsukuba.ac.jp.
  • Kainoh K; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
  • Yoshino R; Transborder Medical Research Center, University of Tsukuba, Tsukuba, Ibaraki, Japan.
  • Hayashi A; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
  • Han SI; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
  • Araki M; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
  • Ohno H; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
  • Takeuchi Y; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
  • Tsuyuzaki T; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
  • Yamazaki D; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
  • Wanpei C; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
  • Hada L; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
  • Watanabe S; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
  • Paramita Adi Putri PI; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
  • Murayama Y; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
  • Sugano Y; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
  • Osaki Y; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
  • Iwasaki H; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
  • Yahagi N; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
  • Suzuki H; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
  • Miyamoto T; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
  • Matsuzaka T; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan; Transborder Medical Research Center, University of Tsukuba, Tsukuba, Ibaraki, Japan.
  • Shimano H; Department of Endocrinology and Metabolism, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
J Biol Chem ; 299(7): 104890, 2023 07.
Article em En | MEDLINE | ID: mdl-37286039
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: PPAR alfa / Oxirredutases do Álcool / Proteínas Correpressoras / Obesidade Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: PPAR alfa / Oxirredutases do Álcool / Proteínas Correpressoras / Obesidade Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão