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Prime editing-based gene correction alleviates the hyperexcitable phenotype and seizures of a genetic epilepsy mouse model.
Cao, Bi-Rong; Huang, Yi-Ming; Tian, Fu-Yun; Li, Jin-Hui; Xu, Chun-Long; Wei, Yu; Liu, Ji-Kai; Guo, Qian-Bei; Xu, Hai-Yan; Zhan, Li; Lv, Rui-Min; Sun, Yi-di; Hu, Xin-de; Gao, Zhao-Bing; Zhou, Chang-Yang.
Afiliação
  • Cao BR; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Huang YM; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Tian FY; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, 200031, China.
  • Li JH; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Xu CL; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China.
  • Wei Y; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, 200031, China.
  • Liu JK; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, 200031, China.
  • Guo QB; Shanghai Immunocan Biotech Co., LTD, Shanghai, 201800, China.
  • Xu HY; Shanghai Immunocan Biotech Co., LTD, Shanghai, 201800, China.
  • Zhan L; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Lv RM; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Sun YD; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Hu XD; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, 200031, China.
  • Gao ZB; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, 200031, China. ydsun@ion.ac.cn.
  • Zhou CY; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, 200031, China. huxinde@ion.ac.cn.
Acta Pharmacol Sin ; 44(11): 2342-2345, 2023 11.
Article em En | MEDLINE | ID: mdl-37402996
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Convulsões / Epilepsia Limite: Animals Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Convulsões / Epilepsia Limite: Animals Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China