Microtiter plate-based chemistry and in situ screening: SuFEx-enabled lead discovery of selective AChE inhibitors.

Tang, Kun; Li, Huan-Huan; Wu, Chengyao; Zhang, Shi-Long; Yang, Jian-Guo; Tang, Wenjian; Qin, Hua-Li

Tang, Kun; Li, Huan-Huan; Wu, Chengyao; Zhang, Shi-Long; Yang, Jian-Guo; Tang, Wenjian; Qin, Hua-Li.

Afiliação

Tang K; School of Pharmacy, Macau University of Science and Technology, Macau, P.R. China.
Li HH; School of Pharmacy, Anhui Medical University, Hefei, P.R. China.
Wu C; School of Pharmacy, Anhui Medical University, Hefei, P.R. China.
Zhang SL; School of Pharmacy, Anhui Medical University, Hefei, P.R. China.
Yang JG; School of Pharmacy, Anhui Medical University, Hefei, P.R. China.
Tang W; School of Pharmacy, Anhui Medical University, Hefei, P.R. China.
Qin HL; School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, Wuhan, P.R. China.

J Enzyme Inhib Med Chem ; 38(1): 2237213, 2023 Dec.

Article em En | MEDLINE | ID: mdl-37501629

Assuntos

Fluoretos; Compostos de Enxofre; Fluoretos/química; Estrutura Molecular; Dor; Sulfonamidas; Enxofre/química

Palavras-chave

SuFEx click chemistry; cholinesterase inhibitor; sulphonamide; sulphonyl fluoride

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos de Enxofre / Fluoretos Tipo de estudo: Diagnostic_studies / Screening_studies Idioma: En Revista: J Enzyme Inhib Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2023 Tipo de documento: Article

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