Continuous Monitoring of the Agglomeration and Sedimentation of Indomethacin Nanosuspensions Using T<sub>2</sub> Relaxation Time with Time-Domain NMR.

Ono, Takashi; Okada, Kotaro; Tsuchiya, Megumi; Hayashi, Yoshihiro; Kumada, Shungo; Onuki, Yoshinori

Continuous Monitoring of the Agglomeration and Sedimentation of Indomethacin Nanosuspensions Using T₂ Relaxation Time with Time-Domain NMR.

Ono, Takashi; Okada, Kotaro; Tsuchiya, Megumi; Hayashi, Yoshihiro; Kumada, Shungo; Onuki, Yoshinori.

Afiliação

Ono T; Laboratory of Pharmaceutical Technology, School of Pharmacy and Pharmaceutical Sciences, University of Toyama.
Okada K; Formulation Development Department, Development & Planning Division, Nichi-Iko Pharmaceutical Co., Ltd.
Tsuchiya M; Laboratory of Pharmaceutical Technology, School of Pharmacy and Pharmaceutical Sciences, University of Toyama.
Hayashi Y; Laboratory of Pharmaceutical Technology, School of Pharmacy and Pharmaceutical Sciences, University of Toyama.
Kumada S; Formulation Development Department, Development & Planning Division, Nichi-Iko Pharmaceutical Co., Ltd.
Onuki Y; Formulation Development Department, Development & Planning Division, Nichi-Iko Pharmaceutical Co., Ltd.

Chem Pharm Bull (Tokyo) ; 71(8): 665-669, 2023.

Article em En | MEDLINE | ID: mdl-37532537

Assuntos

Indometacina; Nanopartículas; Indometacina/química; Tamanho da Partícula; Espectroscopia de Ressonância Magnética; Imageamento por Ressonância Magnética; Nanopartículas/química; Suspensões; Solubilidade

Palavras-chave

NMR relaxation; agglomeration; dispersion analyzer; nanosuspension; sedimentation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Indometacina / Nanopartículas Idioma: En Revista: Chem Pharm Bull (Tokyo) Ano de publicação: 2023 Tipo de documento: Article

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