Allosteric Regulation of Switch-II Domain Controls KRAS Oncogenicity.

Yang, Moon Hee; Tran, Timothy H; Hunt, Bethany; Agnor, Rebecca; Johnson, Christian W; Shui, Bing; Waybright, Timothy J; Nowak, Jonathan A; Stephen, Andrew G; Simanshu, Dhirendra K; Haigis, Kevin M

Yang, Moon Hee; Tran, Timothy H; Hunt, Bethany; Agnor, Rebecca; Johnson, Christian W; Shui, Bing; Waybright, Timothy J; Nowak, Jonathan A; Stephen, Andrew G; Simanshu, Dhirendra K; Haigis, Kevin M.

Afiliação

Yang MH; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Tran TH; Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Hunt B; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Frederick, Maryland.
Agnor R; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Johnson CW; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Shui B; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Waybright TJ; Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Nowak JA; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Stephen AG; Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Simanshu DK; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Frederick, Maryland.
Haigis KM; Department of Pathology, Brigham & Women's Hospital and Harvard Medical School, Boston, Massachusetts.

Cancer Res ; 83(19): 3176-3183, 2023 10 02.

Article em En | MEDLINE | ID: mdl-37556505

Assuntos

Lisina; Proteínas Proto-Oncogênicas p21(ras); Animais; Camundongos; Regulação Alostérica; Fatores de Troca do Nucleotídeo Guanina/metabolismo; Lisina/metabolismo; Mutação; Nucleotídeos/metabolismo; Proteínas Proto-Oncogênicas p21(ras)/genética; Proteínas Proto-Oncogênicas p21(ras)/metabolismo; Proteínas ras/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas p21(ras) / Lisina Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Cancer Res Ano de publicação: 2023 Tipo de documento: Article

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