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A scan of all coding region variants of the human genome, identifies 13q12.2-rs9579139 and 15q24.1-rs2277598 as novel risk loci for pancreatic ductal adenocarcinoma.
Giaccherini, Matteo; Gori, Leonardo; Gentiluomo, Manuel; Farinella, Riccardo; Cervena, Klara; Skieceviciene, Jurgita; Dijk, Frederike; Capurso, Gabriele; Vezakis, Antonis; Archibugi, Livia; Chammas, Roger; Hussein, Tamás; Tavano, Francesca; Hegyi, Péter; Lovecek, Martin; Izbicki, Jakob R; Brenner, Hermann; Mohelnikova-Duchonova, Beatrice; Dell'Anna, Giuseppe; Kupcinskas, Juozas; Ermini, Stefano; Aoki, Mateus Nóbrega; Neoptolemos, John P; Gazouli, Maria; Pasquali, Claudio; Pezzilli, Raffaele; Talar-Wojnarowska, Renata; Oliverius, Martin; Al-Saeedi, Mohammed; Lucchesi, Maurizio; Furbetta, Niccolò; Carrara, Silvia; van Eijck, Casper H J; Maleckas, Almantas; Milanetto, Anna Caterina; Lawlor, Rita T; Schöttker, Ben; Boggi, Ugo; Morelli, Luca; Ginocchi, Laura; Ponz de Leon Pisani, Ruggero; Sperti, Cosimo; Zerbi, Alessandro; Arcidiacono, Paolo Giorgio; Uzunoglu, Faik G; Bunduc, Stefania; Holleczek, Bernd; Gioffreda, Domenica; Malecka-Wojciesko, Ewa; Kiudelis, Mindaugas.
Afiliação
  • Giaccherini M; Department of Biology, University of Pisa, Pisa, Italy.
  • Gori L; Department of Biology, University of Pisa, Pisa, Italy.
  • Gentiluomo M; Department of Biology, University of Pisa, Pisa, Italy.
  • Farinella R; Department of Biology, University of Pisa, Pisa, Italy.
  • Cervena K; Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Prague, Czech Republic.
  • Skieceviciene J; First Faculty of Medicine, Institute of Biology and Medical Genetics, Charles University, Prague, Czech Republic.
  • Dijk F; Department of Gastroenterology, Institute for Digestive Research, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
  • Capurso G; Department of Pathology, Cancer Center Amsterdam, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
  • Vezakis A; Digestive and Liver Disease Unit, S. Andrea Hospital, "Sapienza" University of Rome, Rome, Italy.
  • Archibugi L; Pancreato-Biliary Endoscopy and Endosonography Division, IRCCS San Raffaele Scientific Institute, Pancreas Translational and Clinical Research Center, Vita-Salute San Raffaele University, Milan, Italy.
  • Chammas R; Department of Surgery, Aretaieio Hospital, Medical School, National and Kapodistrian University of Athens, Athens 11528, Greece.
  • Hussein T; Digestive and Liver Disease Unit, S. Andrea Hospital, "Sapienza" University of Rome, Rome, Italy.
  • Tavano F; Pancreato-Biliary Endoscopy and Endosonography Division, IRCCS San Raffaele Scientific Institute, Pancreas Translational and Clinical Research Center, Vita-Salute San Raffaele University, Milan, Italy.
  • Hegyi P; Departamento de Radiologia e Oncologia, Instituto Do Câncer Do Estado de São Paulo (ICESP), Center for Translational Research in Oncology (LIM24), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), São Paulo, Brazil.
  • Lovecek M; Center for Translational Medicine, Semmelweis University, Budapest, Hungary.
  • Izbicki JR; Division of Pancreatic Diseases, Heart and Vascular Center, Semmelweis University, Budapest, Hungary.
  • Brenner H; Division of Gastroenterology and Research Laboratory, Fondazione IRCCS "Casa Sollievo della Sofferenza" Hospital, San Giovanni Rotondo, Foggia, Italy.
  • Mohelnikova-Duchonova B; Center for Translational Medicine, Semmelweis University, Budapest, Hungary.
  • Dell'Anna G; Division of Pancreatic Diseases, Heart and Vascular Center, Semmelweis University, Budapest, Hungary.
  • Kupcinskas J; Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary.
  • Ermini S; Department of Surgery I, University Hospital Olomouc, Olomouc, Czech Republic.
  • Aoki MN; Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Neoptolemos JP; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Gazouli M; Division of Preventive Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Pasquali C; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Pezzilli R; Department of Oncology and Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University and University Hospital, Olomouc, Czech.
  • Talar-Wojnarowska R; Pancreatico/Biliary Endoscopy and Endosonography Division, Pancreas Translational and Clinical Research Center, San Raffaele Scientific Institute, Milan, Italy.
  • Oliverius M; Department of Gastroenterology, Institute for Digestive Research, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
  • Al-Saeedi M; Blood Transfusion Service, Azienda Ospedaliero-Universitaria Meyer, Children's Hospital, Florence, Italy.
  • Lucchesi M; Laboratory for Applied Science and Technology in Health, Carlos Chagas Institute, Oswaldo Cruz Foundation (Fiocruz), Curitiba, Brazil.
  • Furbetta N; Department of General Surgery, University of Heidelberg, Heidelberg, Germany.
  • Carrara S; Department of Basic Medical Sciences, Laboratory of Biology, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
  • van Eijck CHJ; Department of Surgery, Oncology and Gastroenterology-DiSCOG, University of Padova, Padua, Italy.
  • Maleckas A; Potenza County Medical Association, Potenza, Italy.
  • Milanetto AC; Department of Digestive Tract Diseases, Medical University of Lodz, Lodz, Poland.
  • Lawlor RT; Department of Surgery, University Hospital Kralovske Vinohrady, Third Faculty of Medicine, Charles University, Prague, Czech Republic.
  • Schöttker B; Department of General Surgery, University of Heidelberg, Heidelberg, Germany.
  • Boggi U; Department of Medical Oncology, Oncology of Massa Carrara, Azienda USL Toscana Nord Ovest, Carrara, Italy.
  • Morelli L; General Surgery Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
  • Ginocchi L; Endoscopic Unit, Department of Gastroenterology, IRCCS Humanitas Research, Milan, Italy.
  • Ponz de Leon Pisani R; Department of Surgery, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
  • Sperti C; Department of Surgery, Institute for Digestive Research, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
  • Zerbi A; Department of Surgery, Oncology and Gastroenterology-DiSCOG, University of Padova, Padua, Italy.
  • Arcidiacono PG; ARC-Net Centre for Applied Research on Cancer and Department of Diagnostics and Public Health, University of Verona, Verona, Italy.
  • Uzunoglu FG; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Bunduc S; Division of General and Transplant Surgery, Pisa University Hospital, Pisa, Italy.
  • Holleczek B; General Surgery Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
  • Gioffreda D; Department of Medical Oncology, Oncology of Massa Carrara, Azienda USL Toscana Nord Ovest, Carrara, Italy.
  • Malecka-Wojciesko E; Pancreatico/Biliary Endoscopy and Endosonography Division, Pancreas Translational and Clinical Research Center, San Raffaele Scientific Institute, Milan, Italy.
  • Kiudelis M; Department of Surgery, Oncology and Gastroenterology-DiSCOG, University of Padova, Padua, Italy.
Carcinogenesis ; 44(8-9): 642-649, 2023 12 02.
Article em En | MEDLINE | ID: mdl-37670727
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Carcinogenesis Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Carcinogenesis Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália