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Contemporary Clinical Profile of Left-Sided Native Valve Infective Endocarditis: Influence of the Causative Microorganism.
Cabezón, Gonzalo; de Miguel, María; López, Javier; Vilacosta, Isidre; Pulido, Paloma; Olmos, Carmen; Jerónimo, Adrián; Pérez, Javier B; Lozano, Adrián; Gómez, Itzíar; San Román, J Alberto.
Afiliação
  • Cabezón G; Instituto de Ciencias del Corazón (ICICOR), Hospital Clínico, Ciber de Enfermedades Cardiovasculares (CIBERCV), 47003 Valladolid, Spain.
  • de Miguel M; Instituto de Ciencias del Corazón (ICICOR), Hospital Clínico, Ciber de Enfermedades Cardiovasculares (CIBERCV), 47003 Valladolid, Spain.
  • López J; Instituto de Ciencias del Corazón (ICICOR), Hospital Clínico, Ciber de Enfermedades Cardiovasculares (CIBERCV), 47003 Valladolid, Spain.
  • Vilacosta I; Instituto Cardiovascular, Hospital Clínico San Carlos, 28040 Madrid, Spain.
  • Pulido P; Instituto de Ciencias del Corazón (ICICOR), Hospital Clínico, Ciber de Enfermedades Cardiovasculares (CIBERCV), 47003 Valladolid, Spain.
  • Olmos C; Instituto Cardiovascular, Hospital Clínico San Carlos, 28040 Madrid, Spain.
  • Jerónimo A; Instituto Cardiovascular, Hospital Clínico San Carlos, 28040 Madrid, Spain.
  • Pérez JB; Instituto de Investigación Sanitaria del Hospital la Princesa (IIS-IP), Hospital Universitario la Princesa, 28006 Madrid, Spain.
  • Lozano A; Instituto de Ciencias del Corazón (ICICOR), Hospital Clínico, Ciber de Enfermedades Cardiovasculares (CIBERCV), 47003 Valladolid, Spain.
  • Gómez I; Instituto de Ciencias del Corazón (ICICOR), Hospital Clínico, Ciber de Enfermedades Cardiovasculares (CIBERCV), 47003 Valladolid, Spain.
  • San Román JA; Instituto de Ciencias del Corazón (ICICOR), Hospital Clínico, Ciber de Enfermedades Cardiovasculares (CIBERCV), 47003 Valladolid, Spain.
J Clin Med ; 12(17)2023 Aug 22.
Article em En | MEDLINE | ID: mdl-37685509
ABSTRACT
Studies focused on the clinical profile of native valve endocarditis are scarce and outdated. In addition, none of them analyzed differences depending on the causative microorganism. Our objectives are to describe the clinical profile at admission of patients with left-sided native valve infective endocarditis in a contemporary wide series of patients and to compare them among the most frequent etiologies. To do so, we conducted a prospective, observational cohort study including 569 patients with native left-sided endocarditis enrolled from 2006 to 2019. We describe the modes of presentation and the symptoms and signs at admission of these patients and compare them among the five more frequent microbiological etiologies. Coagulase-negative Staphylococci and Enterococci endocarditis patients were the oldest (71 ± 11 years), and episodes caused by Streptococci viridans were less frequently nosocomial (4%). The neurologic, cutaneous or renal modes of presentation were more typical in Staphylococcus aureus endocarditis (28%, p = 0.002), the wasting syndrome of Streptococcus viridans (49%, p < 0.001), and the cardiac in Coagulase-negative Staphylococci, Enterococci and unidentified microorganism endocarditis (45%, 49% and 56%, p < 0.001). The clinical signs agreed with the mode of presentation. In conclusion, the modes of presentation and the clinical picture at admission were tightly associated with the causative microorganism in patients with left-sided native valve endocarditis.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Observational_studies / Risk_factors_studies Idioma: En Revista: J Clin Med Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Espanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Observational_studies / Risk_factors_studies Idioma: En Revista: J Clin Med Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Espanha